Final analysis of a trial of M72/AS01E vaccine to prevent Tuberculosis
The final analysis of a multi-site medical trial involving the University of Cape Town (UCT) has produced the first signal of a potentially effective vaccine against tuberculosis (TB) in almost 100 years.
Phase 3 efficacy study finds shortened 4-month TB drug therapy treatment equivalent to 6-months therapy
The New England Journal of Medicine has published the results of a clinical study which shows that in a randomised phase 3 clinical trial, a shortened 4-month TB treatment was equivalent to the standard 6-month TB treatment.
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New multi-functional TB blood test validated
As part of a global research effort SATVI researchers have developed and validated a new, simple blood-based test to identify healthy people at risk of developing tuberculosis (TB) disease, and identify sub clinical or clinical TB.
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World TB Day 2024: Yes! We can end TB
Join us in marking a pivotal moment in the battle against TB this World TB Day, March 24, 2024.
News from the South African Tuberculosis Vaccine Initiative.
World TB Day
World TB Day is observed annually on March 24, amplifies the need to strengthen our fight against TB, the deadliest infectious disease. TB continues to affect millions globally, inflicting severe health, social, and economic consequences.
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Research Focus: Titan Vaccine Research Project
Dr Munyaradzi Musvosvi speaks about the Titan Vaccine Research Project which will allow the selection of the most promising TB vaccine candidates.
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Shining a spotlight on science
SATVI's Professor Nemes and Doctor Young-Bailie recently participated in Soapbox Science co-hosted by the University of Cape Town (UCT), iThemba LABS, the South African Astronomical Observatory (SAAO), and the V&Alfred Waterfront.
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Latest research: Co-regulation of innate and adaptive immune responses induced by ID93+GLA-SE vaccination in humans
SATVI scholars have co-authored "Co-regulation of innate and adaptive immune responses induced by ID93+GLA-SE vaccination in humans" appearing in the Frontiers in Immunology journal.
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Previous highlights
Video: World TB Day: Vaccine trial inspires SATVI clinicians to imagine a world without TB
On World TB Day, the University of Cape Town (UCT) shines the spotlight on phase three of a clinical trial led by clinicians at the South African Tuberculosis Vaccine Initiative (SATVI).
Download: SATVI 20 year history
The corporate history of the South African Tuberculosis Vaccine Initiative is available online. This history is the result of more than 20 interviews conducted over a period of about one year with SATVI staff and students, including ma
Download: SATVI 2022 Annual Report
The SATVI Annual Report 2022 is available for download.
SATVI researchers amongst the top UCT researchers studying BCG: 1989 - 2021
The University of Cape Town is leading international research into the only licensed TB vaccine, Bacille Calmette-Guerin (BCG), according to a new study.
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