Fogarty HATTP Annual Scientific Meeting 2022
Kathy Wood
25 February 2022
The 3rd Annual Scientific Meeting of the HIV-associated TB Training Program was held on Friday 25th February 2022 in the Neuroscience Auditorium at Groote Schuur Hospital. The meeting was held in a hybrid format with local fellows and members of the local Administrative Committee attending in person, and our US collaborators, one of the fellows and a Committee member connecting remotely via Zoom.
The program started with an introduction and summary of the HATTP activities to date by the Principal Investigator, Graeme Meintjes. This was followed by research project presentations from 11 of the 16 fellows who have been supported by HATTP.
Zinhle Cindi: Pharmacogenetics of dolutegravir plasma exposure among Southern Africans living with HIV
Simon Mendelsohn: Head-to-head validation of blood transcriptomic biomarkers for pulmonary TB by PCR
Mmamapudi Kubjane: The impact of HIV and TB interventions on South African adult TB trends, 1990 2019: a mathematical modelling analysis
Avuyonke Balfour: The effect of HIV, Tuberculosis and Tuberculosis treatment on the frequencies and activation profiles of antigen presenting cells
Linda Boloko: Longitudinal blood and urine TB treatment response biomarkers
Tafadzwa Chimbetete: The immunological profile of the skin in DRESS and SJS/TEN reactions to first-line tuberculosis drugs in HIV infected patients
Phuti Choshi: HLA Class I alleles associated with anti-tuberculosis drugs induced severe cutaneous adverse drug reactions
Hygon Mutavhatsindi: Inflammatory profile of soluble markers in blood and at the site of disease in pericardial TB patients
Mahmoud Abdelwahab: Population PK modelling of Linezolid in South African adults with MDR TB and HIV co-infection
Raymond Moseki: Whole blood RNA sequencing in patients with paradoxical Tuberculosis associated Immune Reconstitution Inflammatory Syndrome: An Exploratory Analysis
Rephaim Mpofu: Renal toxicity associated with TDF and TAF in a South African population – PK-PD analysis
We were also fortunate that Professor Marc Blockman, Chair of the UCT Human Research Ethics Committee (HREC) presented a plenary entitled Protection of participants-some thoughts providing the fellows with thought-provoking examples of ethical dilemmas and emphasising the importance of utilising the experience and advice of the HREC.
Everyone was pleased to be able to meet in person again, with COVID-19 protocols in place.
