Department of Anaesthesia & Perioperative Medicine

Research Publications November 2019 – November 2020

Book Chapters

  1. Swanevelder J, Roscoe, A.J. Comprehensive TOE Examination. Chapter in: Core Topics in Cardiac Anaesthesia, 3rd edition, 2020; Page 239-241. Edited by Joseph Arrowsmith, Andrew Roscoe, Jonathan Mackay. Cambridge University Press

Peer-reviewed publications

  1. Ally M, Cloete E. Reed AR. A prospective clinical audit to evaluate postoperative quality of recovery in adults at New Somerset Hospital, Cape Town, South Africa.  S Afr Med J 2020;110(10):1036-1040
     
  2. Alphonsus CS, Govender P, Rodseth RN, Biccard BM. The role of cardiac rehabilitation using exercise to decrease natriuretic peptide levels in non-surgical patients: a systematic review. Perioper Med (Lond). 2019 Nov 18; 8:4. doi: 10.1186/s13741-019-0124-0. PMID: 31832178; PMCID: PMC6859626.

  1. Alphonsus CS, Govender P, Rodseth RN, Biccard BM. Natriuretic peptide-directed medical therapy: a systematic review. Perioper Med (Lond). 2020 Feb 18; 9:5. doi: 10.1186/s13741-019-0134-y. PMID: 32095234; PMCID: PMC7027249.
  2. Ayebale AET, Kassebaum NJ, Roche AM, Biccard BM. Africa’s Critical Care Capacity before COVID-19. South Afr J Anaesth Analg 2020; 26: 162-4.
  3. Bekker LG, Delany-Moretlwe S, Biccard B, du Toit L et al. Protecting healthcare workers: A critical part of the COVID-19 response. S Afr Med J 2020 – published online ahead of print
  4. Biccard BM, HIP ATTACK Investigators. Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial. The Lancet 2020 Feb 29;395(10225):698-708. doi: 10.1016/S0140-6736(20)30058-1. Epub 2020 Feb 9.PMID: 32050090
  5. Biccard BM, APORG Working Group. Priorities for peri-operative research in Africa. Anaesthesia 2020, 75 (Suppl.1); e28-e33.
  6. Buthelezi AS, Bishop DG, Rodseth RN, Dyer RA. Prophylactic phenylephrine and fluid co-administration to reduce spinal hypotension during elective caesarean section in a resource-limited setting: a prospective alternating intervention study. Anaesthesia. 2020 Apr;75(4):487-492. doi: 10.1111/anae.14950. Epub 2019 Dec 6. PMID: 31811659.
  7. Chabilall JA, Thomas J, Hofmeyr R. Foreign body ingestion in children presenting to a tertiary paediatric centre in South Africa: A retrospective analysis focusing on battery ingestion. SAMJ 2020; 110(7): 652-656.
  8. Chu KM, Naidoo M, Klopper JH, Kloppers JC, Navsaria P, Reed A. The contribution of first-level hospitals to 6 essential surgical procedures in a South African health district: A retrospective, cross-sectional study. East and Central African Journal of Surgery. Oct 2020
  9. Conradie WS, Biesman-Simons T, Roodt F, Nejthardt M, Davids J, Pretorius T, Davies G, Cloete E, Fullerton Z, Roos J, Flint M, Swanevelder JL, Dyer RA, Biccard BM. A multicentre prospective observational study of the prevalence of preoperative anaemia and iron deficiency in adult elective surgical patients in hospitals in Western Cape Province, South Africa. SAMJ 2020; 110(1): 65-68.
  10. COVIDSurg Collaborative. Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans. Br J Surg. 2020 May 12:10.1002/bjs.11746. doi: 0.1002/bjs.11746. Epub ahead of print. PMID: 32395848; PMCID: PMC7272903.
  11. Delisle M, Pradarelli JC, Panda N, Biccard B, et al. Variation in global uptake of the Surgical Safety Checklist. BJS 2020; 107:e151-e160.
  12. Duceppe E, Patel A, Chan MTV, Rodseth R, Biccard B, et al. Preoperative N-Terminal Pro-B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery. Ann Intern Med 2020 Jan 21;172(2):96-104. doi: 10.7326/M19-2501. Epub 2019 Dec 24.PMID: 31869834.
  13. El-Boghdadly K, Wong DJN, Owen R, et al. Risks to healthcare workers following tracheal intubation of patients with COVID-19: a prospective international multicentre cohort study. Anaesthesia 2020 Jun 9;10.1111/anae.15170. doi:10.1111/anae.15170. Online ahead of print.
  14. Evered L, Biccard B. A call to action: evaluation of perioperative neurocognitive disorders in low- and middle-income countries. Br J Anaesth 2020 Aug 7;S0007-0912(20)30568-7. doi: 10.1016/j.bja.2020.06.065.
  15. Fagan JJ, Cairncross L, Biccard B, Fieggen G, Maswime S. COVID-19 exposes health worker shortages in the USA and UK, but nationalism and self-interest must not exploit medical workforces from low- and middle-income countries. S Afr Med J 2020; 110: 335.
  16. Gordon C, Gordon PC. Handmaidens and pioneers: Three female anaesthetists and their contribution to anaesthesia in South Africa. S Afr Med J 2020;110(11): 1088-1092
  17. Gordon PC, James MF. The Nagin Parbhoo History of Anaesthesia Museum – Part 1. South Afr J of Anaesth  Analg 2019; 25(6): 5-13
  18. Gordon PC, Fagan JJ. Obituary- Jan Daniel Smith, 6 February 1939 – 6 September 2019. S Afr Med J 2020; 110(3).
  19. Groenewald MB, van Nugteren J, Parker R. Are Groote Schuur Hospital anaesthesiologists burnt out? A cross-sectional study of prevalence and risk. South Afr J Anaesth Analg 2020; 26(3:) 155-161.
  20. HIP ATTACK Investigators. Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial. Lancet. 2020 Feb 29;395(10225):698-708. doi: 10.1016/S0140-6736(20)30058-1. Epub 2020 Feb 9. PMID: 32050090.

  1. Hofmeyr R, Bester K, Willms A, Hewitson J, Byhahn C.  Tracheosophageal fistula following button battery ingestion in an infant.  Der Anaesthetist 2019; 68 (11) 777-779
  2. Hofmeyr R, Biccard BM. Now, more than ever, is the time for evidence-based medicine. South Afr J Anaesth Analg 2020; 26: 113-5.
  3. Hofmeyr R, Llewellyn R, Fagan JJ. Multidisciplinary difficult airway challenges: Perioperative management of glottic and supraglottic tumors. Operative Techniques in Otolaryngology 2020; 31: 120-127.
  4. Hofmeyr R, Lubbe D. Innovation in endoscopic management of tracheal stenosis. Abstracts/Trends in Anaesthesia and Critical Care 2020; 30: e1-192.
  5. Hofmeyr R, McGuire J, Marwick P, Park K, Proxenos M, Lehmann M, Weich H.  Assessment of continuous ventilation during tracheal dilatation using a novel, non-occlusive balloon in an ovine model.  South Afr J Anaesth Analg 2020; 26(4):21-24.
  6. Hofmeyr R, Alphonsus C, de Villiers C, Eave D. Innovation in low-cost videolaryngoscopy: Intubator V1-Indirect compared with Storz C-Mac in a simulated difficult airway. Abstracts/Trends in Anaesthesia and Critical Care 2020; 30: e1-192.
  7. Hofmeyr R. Methoxyflurane: inspiration of the old to breathe life into the new. South Afr J Anaesth Analg 2020; 26(5)
  8. Imamdin A, Hadebe N, Lecour S. SAFE pathway and conditioning: from discovery to its effectiveness in the presence of cardiovascular risk factors. Conditioning Medicine 2020; 3(2) 98-103
  9. Jacobs NF, Veronese LR, Okano S, Hurst C, Dyer RA. The incidence of postoperative nausea and vomiting after caesarean section in patients with hyperemesis gravidarum: a retrospective cohort study. International Journal of Obstetric Anesthesia (2020) 44, 81-89.

  1. James MF, Gordon PC. The Nagin Parbhoo History of Anaesthesia Museum Part 2. South Afr J Anaesth Analg 2020; 26(3): 128-130

  1. Johnson R, Nxele X, Cour M, Sangweni N, Jooste T, Hadebe N, et al. Identification of potential biomarkers for predicting the early onset of diabetic cardiomyopathy in a mouse model. Scientific Reports (2020) 10:12352

  1. Jordaan M, Reed AR, Cloete E, Dyer RA. A retrospective audit of anaesthesia for caesarean section in parturients with eclampsia at a tertiary referral hospital in Cape Town. South Afr J Anaesth Analg 2020; 26: 192-7.
  2. Kgokong D, Parker R. Physical activity in physiotherapy students: Levels of physical activity and perceived benefits and barriers to exercise. South African Journal of Physiotherapy 2020; 76(1), a1399.
  3. Kluyts H-L, Conradie W, Cloete E, Reed A, Davies GL, Biccard B et al. Development of a Clinical Prediction Model for In-hospital Mortality from the South African Cohort of the African Surgical Outcomes Study. World J Surg 2020 doi.org/10.1007/s00268-020-05843-1
  4. Limakatso K, Bedwell GJ, Madden VJ, Parker R. The prevalence and risk factors for phantom limb pain in people with amputations: A systematic review and meta-analysis. PLoS ONE 15(10): e0240431
  5. Lindermann J, du Toit L, Kotze U et al. Survival equivalence in patients treated for borderline resectable and unresectable locally advanced pancreatic ductal adenocarcinoma: a systematic review and network meta-analysis. HPB https://doi.org/10.1016/j.hpb.2020.09.022
  6. Lourens A, Parker R, Hodkinson P. Prehospital acute traumatic pain assessment and management practices in the Western Cape, South Africa: a retrospective review. International Journal of Emergency Medicine 2020; 13:21.
  7. Lourens A, Hodkinson P, Parker R. Acute pain assessment and management in the prehospital setting, in the Western Cape, South Africa: a knowledge, attitudes and practices survey. Int J Emerg Med 2020 May 5;13(1):21 doi: 10.1186/s12245-020-00278-w.
  8. Madden VJ, Parker R, Goodin BR. Chronic pain in people with HIV: a common comorbidity and threat to quality of life. Pain Manag. 2020 Jul;10(4):253-260. doi: 10.2217/pmt-2020-0004. Epub 2020 Jun 2
  9. Mashanda-Tafaune B, van Nugteren J, Parker R. Pain knowledge and attitudes of final-year medical students at the University of Cape Town: A cross-sectional survey. Afr J Prim Health Care Fam Med 2020 Jul 30;12(1): e1-e6. doi: 10.4102/phcfm. v12i1.2306.
  10. Massalha S, Walpot J, Dey D, Guler EC, Clarkin O, Godkin L, Ratnayake I, Jayasinghe P, Hossain A, Crean A, Chan M, Butler C, Tandon V, Nagele P, Woodard PK, Mrkobrada M, Szczeklik W, Abdul Aziz YF, Biccard B, Devereaux PJ, Sheth T, Chow BJW. Epicardial Adipose Tissue: An Independent Predictor of Post-Operative Adverse Cardiovascular Events (CTA VISION Substudy). JACC Cardiovasc Imaging. 2020 Mar;13(3):882-884. doi: 10.1016/j.jcmg.2019.09.017. Epub 2019 Nov 13. PMID: 31734207.
  11. Mayeza S, Arcache MJ, Loo L, Dyer RA. Coagulation in the HIV positive patient: a thromboelastography study. South Afr J Anaesth Analg 2020; 26: 188-91.
  12. Mendelson M, Booysens L, Boutall A, Hofmeyr R, Joubert I et al. The mechanics of setting up a COVID-19 response: Experiences of the COVID-19 epidemic from Groote Schuur Hospital, Cape Town, South Africa. S Afr Med J 2020 doi.org/10.7196/SAMJ.202.v110i10.15215
  13. Mendelson M, Boloko L, Boutall A, Hofmeyr R et al. Clinical Management of COVID-19: Experiences of the COVID-19 epidemic at Groote Schuur Hospital. S Afr Med J 2020;110(10)
  14. Meyer HM, Torborg A, Cronje L, et al. The association between preoperative anaemia and postoperative morbidity in paediatric surgical patients: A secondary analysis of a prospective observational cohort study. Paediatr Anaesth 2020 Apr 10. doi: 10.1111/pan.13872. Online ahead of print.PMID: 32275796
  15. Muhly WT, Taylor E, Razavi C, Meyer H et al. A systematic review of the outcomes reported in pediatric perioperative research: A report from the Pediatric Perioperative Outcomes Group. Pediatric Anesthesia 2020;00:1-17
  16. National Institute for Health Research Global Research Health Unit on Global Surgery. Delphi prioritization and development of global surgery guidelines for the prevention of surgical-site infection. Br J Surg. 2020 Jul;107(8):970-977. doi: 10.1002/bjs.11530. Epub 2020 Mar 24. PMID: 32212158; PMCID: PMC7317442.
  17. Ortner CM, Macias P, Neethling E, Krishnamoorthy V, Carvalho B, Swanevelder JL, Dyer RA. Ocular sonography in pre-eclampsia: a simple technique to detect raised intracranial pressure? International Journal of Obstetric Anesthesia 2020; 41: 1-6.
  18. Parker R, Madden VJ. State of the art: What have the pain sciences brought to physiotherapy? South African Journal of Physiotherapy 2020; 76(1): a1390.
  19. Pfister CL, Govender S, Dyer RA, et al. A Multicenter, Cross-Sectional Quality Improvement Project: The Perioperative Implementation of a Hypertension Protocol by Anesthesiologists. Anesth Analg 2020 Jul 2. doi: 10.1213/ANE.0000000000004966. Online ahead of print.
  20. Plenge U, Parker R, Davids S, Davies GL, Fullerton Z et al. Quality of recovery after total hip and knee arthroplasty in South Africa: a national prospective observational cohort study. BMC Musculoskeletal Disorders 2020; 21:721
  21. Prempeh ABA, Scherman J, Swanevelder JL. Transesophageal echocardiography in minimally invasive cardiac surgery. Current Opinion in Anaesthesiology 2020; 33(1): 83-91.
  22. Prempeh ABA, Duys R, de Vaal A, Parker R. Pain assessment and management: An audit of practice at a tertiary hospital. Health SA Gesondheid 2020; 25(0); a1281.
  23. Reddy CL, Makasa EM, Biccard B, Smith M, Steyn E, Fieggen G, Maswime S, Meara JG, Chu K. Surgery as a component of universal healthcare: Where is South Africa? S Afr Med J. 2019 Aug 28;109(9):624-625. doi: 10.7196/SAMJ 2019.v109i9.14233. PMID: 31635583.

  1. Roshanov PS, Guyatt GH, Tandon V, et al. Preoperative prediction of Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study. Br J Anaesth 2020 Jul 24: S0007-0912(20)30538-9. doi: 10.1016/j.bja.2020.02.028. Online ahead of print.PMID: 32718723.

  1. Roshanov PS, Eikelboom JW, Sessler DI, et al. Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study establishing diagnostic criteria and prognostic importance. Br J Anaesth 2020 Aug 4: S0007-0912(20)30536-5. doi: 10.1016/j.bja.2020.06.051. Online ahead of print.PMID: 32768179.

  1. Santhirapala V, Peden CJ, Meara JG, Biccard BM, Gelb AW, Johnson WD, Lipnick MS, Makasa EM, Martin J, Maswime S, Mellin-Olsen J, McClain CD. Towards high-quality peri-operative care: a global perspective. Anaesthesia. 2020 Jan;75 Suppl 1: e18-e27. doi: 10.1111/anae.14921. PMID: 31903566.

  1. Scott-Beattie W, Lalu M, Bocock M, Biccard B et al. Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes. Br J Anaesth 2020 – in press

  1. Sessler DI, Biccard BM, (POISE-2 Investigators), et al. One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery. Anesthesiology 2020 Apr;132(4):692-701. doi: 10.1097/ALN.0000000000003158.

  1. Smit M, du Toit L, Lombard C, van Dyk D, Reed A, Dyer R, Hofmeyr R. Desaturation during airway management in pregnancy-related hypertension: Analysis of the obstetric airway management Registry (OBAMR). Abstracts/Trends in Anaesthesia and Critical Care 2020; 30: e1-192.

  1. Smit MI, van Tonder C, du Toit L, van Dyk D, Reed AR, Dyer RA, Hofmeyr R. Validation and initial description of the prospective Obstetric Airway Management Registry (ObAMR). Abstracts/Trends in Anaesthesia and Critical Care 2020; 30:e70

  1. Smit MI, van Tonder C, du Toit L, van Dyk D, Reed AR, Dyer RA, Hofmeyr R. Implementation and initial validation of a multicentre obstetric airway management registry. South Afr J Anaesth Analg 2020; 26: 198-205.

  1. Sorbello M, Cataldo R, Di Giancinto I, Falcetta S, Cortese G, Zdravkovic I, Hofmeyr R.  Barrier enclosure systems and COVID-19: sealing and suction might not be enough. Minerva Anestesiologica 2020, accepted, in press.

  1. Sorbello M, Rosenblatt W, Hofmeyr R, Greif T, Urdenata F.  Opening Pandora’s Box: Aerosol boxes and barrier enclosures for airway management in COVID-19 patients - a scoping review and narrative synthesis. Brit J Anaes 2020; 125 (6) 880-894.

  1. Stegmann G, Llewellyn R, du Toit L, Hofmeyr R. Global airway management of the unstable cervical spine survey. Abstracts/Trends in Anaesthesia and Critical Care 2020; 30: e1-192.
  2. Taylor EH, Hofmeyr R, Torborg A, et al. Risk factors and interventions associated with mortality or survival in adult COVID-19 patients admitted to critical care: a systematic review and meta-analysis. South Afr J Anaesth Analg 2020; 26: 116-27.
  3. Thomas S, Borges F, Bhandari M, et al. Association Between Myocardial Injury and Cardiovascular Outcomes of Orthopaedic Surgery: A Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Substudy. J Bone Joint Surg Am 2020; 102: 880-8.
  4. Tomlinson JMB, Bishop DG, Hofmeyr R, Cronje L, Rodseth RN.  The incidence and predictors of hypoxaemia during induction of general anaesthesia for caesarean delivery in two South African Hospitals: a prospective, observational, dual-centre study.  South Afr J Anaesth Analg 2020; 26(4):183-187
  5. Wei H, Jiang B, Behringer EC, Hofmeyr R et al. Controversies in airway management of COVID-19 patients: updated information and international expert consensus.Brit J Anaes 2020; DOI:http://doi.org/10.1016/j/bja.2020.10029
  6. Wise R, Gibbs M. Blood product usage. South Afr J Anaesth Analg 2020; 26(1): 6-8.
  7. Wise R, Gibbs MW, Louw VJ. Lockdown and our national supply of blood products. S Afr Med J 2020 Apr 2;110(5):12904. doi: 10.7196/SAMJ. 2020. v110i5.14749.
  8. Zdravkovic et al (incl. Hofmeyr).  Perceptions of gender equity in departmental leadership, research opportunities, and clinical work attitudes: an international survey of 11781 anaesthesiologists.  Brit J Anaes 2020; 124(2):160-170.