Department of Anaesthesia & Perioperative Medicine

Research Publications 2021

Book Chapters

  1. More notable names in anaesthesia – (2 book chapters - Prof Gordon)
    Nagin Parbhoo History of Anaesthesia Museum and Memorial Lecture – Nagin Parbhoo (1942-2009)
    Benjamin Weinbren Memorial Lecture – Benjamin Weinbren (1889-1965)

Peer-reviewed publications

  1. Alphonsus CS, Jagga M, Crowther M, Coetzee E, Davies G, Fullerton Z, et al. A prospective observational study of preoperative natriuretic peptide testing in adult non-cardiac surgical patients in hospitals in Western Cape Province, South Africa. S Afr Med J 2021;111(4): 338-342
  2. Alphonsus CS, Motshabi Chakane P, Firfiray L, van der Westhuizen J, Spijkerman S, Cloete NJ, Nejthardt MB. South African cardiovascular risk stratification guideline for non-cardiac surgery. S Afr Med J 2021;111(10b):1019: 1025
  3. Beattie WS, Lalu M, Bocock M, Feng S, Biccard B et al. Systematic review and consensus definitions for the Standarized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes. British Journal of Anaesthesia 2021; 126(1):56-66
  4. Biccard BM, The African COVID-19 Critical Care Outcomes Study (ACCCOS) Investigators. Patient care and clinical outcomes for patients with COVID-19 infection admitted to African high-care or intensive care units (ACCCOS): a multicentre, prospective, observational cohort study. Lancet 2021; 397: 1885-94
  5. Biccard BM, GlobalSurg Collaborative and National Institute for Health Research Global Health Research Unit on Global Surgery. Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries. Lancet 2021; 397:387-97
  6. Biccard BM, PRISM trial Group. Postoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre, open-label, randomised, phase 3 trial. The Lancet Respiratory Medicine 2021; 9: 1221-30
  7. Biccard BM, du Toit L, Lesosky M, et al. Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial. The Lancet Global Health 2021; 9: e1391-e401
  8. Biccard BM, Msosa V, Samateh AL. Prevention of surgical infection in low-resource settings. Lancet 2021; 398: 1664-5
  9. Bonaconsa C, Mbamalu O, Mendelson M, Joubert I, et al. Visual mapping of team dynamics and communication patterns on surgical ward rounds: an ethnographic study. BMJ Qual Saf 2021;0:1-13
  10. Breedt DS, Odland ML, Bakanisi B, et al. Identifying knowledge needed to improve surgical care in Southern Africa using a theory of change approach. BMJ global health 2021; 6
  11. Bruce L, Gunston G, Myburgh A, et al. The Anatomy of the Eustachian Valve – navigating the implications for right-sided surgical and transcatheter cardiac interventions. Journal of Cardiothoracic and Vascular Anesthesia (2020), doi:
  12. Chappell D, van der Linden P, Ripolles-Melchor J, James MFM. Safety and efficacy of tetrastarches in surgery and trauma: a systematic review and meta-analysis of randomised controlled trials. British Journal of Anaesthesia 2021; 127: 556-68
  13. Chaves TC, Stanton TR, Grant A, Pulling BW, Madden VJ et al. Imprecise Visual Feedback About Hand Location Increases a Classically Conditioned Pain Expectancy Effect. Journal of Pain 2021;22(16):748-761
  14. Coetzee E, Absalom AR. Stability of BIS with Schnider or modified Marsh effect-site targeted infusions: As you like it, or much ado about nothing? South Afr J Anaesth Analg 2021; 27 (2): 64-68
  15. Davies JI, Gelb AW, Gore-Booth J, et al. Global surgery, obstetric, and anaesthesia indicator definitions and reporting: An Utstein consensus report. PLoS Med 2021; 18: e1003749
  16. De Villiers CT, Alphonsus C, Eave D, et al. Innovation in low-cost video-laryngoscopy: Intubator V1-Indirect compared with Storz C-MAC in a simulated difficult airway*. Trends in Anaesthesia and Critical Care 2021. In press.
  17. Duys R. Park-Ross J, van Straaten D, Grant E, Copley C. WhatsApp and Internet Protocol messaging in healthcare: a transformative opportunity. South Afr J Anaesth Analg 2021;27(2) 60-62
  18. NIHR Global Health Research Unit on Global Surgery, incl Biccard B. Feasibility and diagnostic accuracy of Telephone Administration of an adapted wound heaLing QuestiONnaire for assessment for surgical site infection following abdominal surgery in low and middle-income countries (TALON): protocol for a study within a trial (SWAT). Trials 2021; 22: 471
  19. Govender S, Pfister C, Rayner B, Dyer RA, Flint M, et al. A multicentre cross-sectional descriptive study evaluating the cardiovascular risk profile of preoperatively identified patients with hypertension. S Afr Med J 2020;111(1):74-79
  20. Gray RM, Evans FM. Well-being of the global anesthesiologist. Pediatric Anesthesia 2021;31:13-15
  21. Herselman, R, Lalloo V, Ueckermann C, van Tonder DJ, Jager E, Spijkerman S, van der Merwe W Pisane M, Hattingh F, Stanton D, Hofmeyr R. Adapted full-face snorkel masks as an alternative for COVID-19 personal protection during aerosol generating procedures in South Africa: A multi-centre, non-blinded in-situ simulation study. African Journal of Emergency Medicine, 2021; 11 (4): 436-441
  22. Hofmeyr R, Elhouni A. Endoscopic airway equipment part 1: physical principles. Southern African Journal of Anaesthesia and Analgesia. 2020 Nov 4;26(6 Suppl 3): S66-69.
  23. Hofmeyr R, Elhouni A. Endoscopic airway equipment part 2: equipment overview. Southern African Journal of Anaesthesia and Analgesia. 2020 Nov 4;26(6 Suppl 3): S70-74.
  24. Hofmeyr R, Sorbello M. Airway management in COVID-19: Time to start thinking outside the box? South Afr J Anaesth Analg 2021;27(1): 4-11
  25. Hofmeyr R, Pereira AI, Zdravkovic I, et al. On strife, natural selection and success in airway management during the COVID-19 pandemic: Shifting from best guess to best practice. Trends in Anaesthesia and Critical Care 2021; 40: 1-3
  26. Hofmeyr R, Seymour LM, Peters S, Petersen A, Swanevelder J. The Role of Anaesthesiologists in the COVID-19 Pandemic: Practical lessons from Groote Schuur Experience. WFSA 2021: doi:10.1029/WFSA-D-21-00001
  27. Hofmeyr R, Rees K, Douglas S et al. Not so clear cut: Cultivating successful surgical cricothyroidotomy. Trends in Anaesthesia and Critical Care. In press.
  28. Jackson K, Wadley AL, Parker R. Managing pain in HIV/AIDS: a therapeutic relationship is as effective as an exercise and education intervention for rural amaXhosa women in South Africa. BMC Public Health (2021) 21:302
  29. Jacobs NF, Veronese LR, Okano S, Hurst C, Dyer RA. The incidence of postoperative nausea and vomiting after caesarean section in patients with hyperemesis gravidarum: a retrospective cohort study. Int J Obstet Anesth. 2020 Nov; 44:81-89. doi: 10.1016/j.ijoa.2020.07.003. Epub 2020 Jul 19. PMID: 32823251.
  30. Jonas E, Biccard BM. Obesity and surgery in general. South African Journal of Surgery 2021; 59: 38-40
  31. Kachapila M, Ademuyiwa AO, Biccard BM, et al. Preliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa. PLoS One 2021; 16: e0254698
  32. Kathrada MIS, Jagga M, Mzoneli YN , Justiaan Swanevelder J, Gibbs MW. Peri-operative Ultrasound among South African Anaesthetists:  A survey of current practice and availability. South Afr J Anaesth Analg. 2021 Vol 6
  33. Kemp, K., 2021. 22q11.2 deletion syndrome: an anaesthetic perspective Southern African Journal of Anaesthesia and Analgesia27(5), 206-210.
  34. Kluyts HL, Biccard BM. The role of peri-operative registries in improving the quality of care in low-resource environments. Anaesthesia 2021; 76: 888-91
  35. Kluyts HL, Conradie W, Cloete E et al. Development of a Clinical Prediction Model for In-hospital Mortality from the South African cohort of the African Surgical Outcomes Study. World Journal of Surgery 2021; 45(2):404-416
  36. Lamy A, Tong W, Mian R, et al. The Cost Implications of Dabigatran in Patients with Myocardial Injury After Non-Cardiac Surgery. Am J Cardiovasc Drugs 2021
  37. Lapere C, Gray R, Wilson G. Paediatric out-of- theatre procedural sedation at a tertiary children’s hospital: A prospective observational study. S Afr J Child Health 2020; 15(1):33-37
  38. Limakatso K, Parker R. Treatment Recommendations for Phantom Limb Pain in People with Amputations: An Expert Consensus Delphi Study.PM R 2021 Nov;13(11):1216-1226
  39. Lindemann J, du Toit L, Kotze U et al. Survival equivalence in patients treated for borderline resectable and unresectable locally advanced pancreatic ductal adenocarcinoma: a systematic review and network meta-analysis. HBP 2021; 23(2):173-186
  40. Lourens A, Parker R, Hodkinson P. Emergency care providers’ perspectives of acute pain assessment and management in the prehospital setting, in the Western Cape, South Africa: A qualitative study. International Emergency Nursing 58 (2021):101042
  41. Majangara, M.B.M., Limakatso, K. and Parker, R., 2021. Patient satisfaction at the Chronic Pain Management Clinic at Groote Schuur Hospital. Southern African Journal of Anaesthesia and Analgesia27(5), 241-248.
  42. Mendelson M, et al incl Hofmeyr R, Joubert I. Clinical management of COVID-19: experiences of the COVID-19 epidemic from groote schuur hospital, Cape Town, South Africa. SAMJ: South African Medical Journal. 2020; 110(10):973-981
  43. Merlin JS, Hamm M, de Abril Cameron F, Madden VJ, Parker R, et al. SPECIAL ISSUE HIV and CHRONIC PAIN (The Global Task Force for Chronic Pain in People with HIV (PWH): Developing a research agenda in an emerging field). AIDS Care. DOI: 10.1080/09540121.2021.1902936
  44. Michell WL, Joubert I, Peters S, Fredericks D, Miller M, Piercy J. The organisational response of a hospital critical care service to the COVID-19 pandemic: The Groote Schuur Hospital experience. Southern African Journal of Critical Care 37(2) 63-69
  45. Morton B, Vercueil A, Masekela R, et al incl Biccard B. Consensus statement on measures to promote equitable authorship in the publication of research from international partnerships. Anaesthesia; 2021:
  46. Munsaka EF, van Dyk D, Parker R. A retrospective audit of pain assessment and management post-caesarean section at New Somerset Hospital in Cape Town, South Africa. S Afr Fam Pract 2021;63(1), a5320
  47. Neethling C, Calligaro G, Miller M, Opie JJS. The evolution of clot strength in critically-ill COVID-19 patients: a prospective observational thromboelastography study. Thrombosis Journal (2021)19:83
  48. Oodit R, Biccard B, Nelson G, Ljungqvist O, Brindle ME. ERAS Society Recommendations for Improving Perioperative Care in Low- and Middle-Income Countries Through Implementation of Existing Tools and Programs: An Urgent Need for the Surgical Safety Checklist and Enhanced Recovery After Surgery. World J Surg 2021; 45: 3246-8
  49. Opperman CJ, Khan F, Piercy JL, Samodien N. Barriers to disinfection of mobile touch screen devices amongst a multidisciplinary team in intensive care units at a tertiary hospital. GERMS 2021; 11(2); 329-336
  50. Roelofse J, Jansen van Rensburg M,Gray R, Lapere C.  SASA paediatric guidelines for the safe use of procedural sedation and analgesia for diagnostic and therapeutic procedures in children: 2021-2026.    South Afr J Anaesth Analg 2021;27(4 Supplement 2): S1-83
  51. Roshanov PS, Sessler DI, Chow CK, et al, incl Biccard B. Predicting myocardial injury and other cardiac complications after elective noncardiac surgery with the Revised Cardiac Risk Index: the VISION study. Can J Cardiol 2021; 37: 1215-24
  52. Roshanov PS, Eikelboom JW Sessler DI, Biccard BM et al. Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study establishing diagnostic criteria and prognostic importance. British Journal of Anaesthesia 2021; 126(1): 163-171
  53. Roshanov PS, Guyatt GH, Tandon V, Borges FK, Lamy A, Whitlock R, Biccard BM et al. Preoperative prediction of Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study. British Journal of Anaesthesia 2021; 126(1): 172-180
  54. Samuel JP, Reed A. The costing of operating theatre time in a secondary-level state sector hospital: A quantitative observational study. S Afr Med J 2021;111(6): 595-600
  55. Smit MI, du Toit L, Dyer RA, van Dyk D, Reed AR, Lombard CJ, Hofmeyr R. Hypoxaemia during tracheal intubation in patients with hypertensive disorders of pregnancy: analysis of data from an obstetric airway management registry. Int J Obstet Anesth. 2021; 45: 41-48.
  56. Taylor EH, Marson EJ, Elhadi M, et al. Factors associated with mortality in patients with COVID-19 admitted to intensive care: a systematic review and meta-analysis. Anaesthesia 2021; 76: 1224-32
  57. Van Dyk D. Starvation in the midst of plenty… of caesarean deliveries. South Afr J Anaesth Analg 2021;27(4):164-166
  58. Veronese L, Swanevelder J, Brooks A. Anaesthesia for the child with a univentricular heart: a practical approach. South Afr J Anaesth Analg 2021;27(3): 144-153
  59. Vickery N, Stephens T, du Toit L, et al. Understanding the performance of a pan-African intervention to reduce postoperative mortality: a mixed-methods process evaluation of the ASOS-2 trial. British Journal of Anaesthesia 2021; 127: 778-88
  60. Wei H, Jiang B, Behringer C, Hofmeyr R, et al. Controversies in airway management of COVID-19 patients: updated information and international expert consensus recommendations. British Journal of Anaesthesia (2021) 126(2): 361-366