I am a clinical pharmacologist and HIV physician who has been working with HIV-infected patients in clinical trials and observational cohorts since 1997. l head the successful Desmond Tutu HIV Centre (DTHC) Treatment Division through leadership of the Groote Schuur Clinical Research Site (GSH-CRS), the DTHC Clinical Trials Unit and the DTHC Gugulethu Research Offices. I have been principal and co-investigator on more than 25 clinical trials of antiretroviral drugs and vaccines, including a range of efficacy, toxicity and dosing studies, both pharmaceutical and investigator-driven. My particular interests are in HIV pharmacology, adherence/retention in care and resistance to ART and I have an extensive publication record in these fields.

I have in-depth experience of conducting research in both state-of-the-art research facilities at the University of Cape Town, including the CRS which is a HPTN and HVTN-affiliated site, as well as in primary health care clinic environments, such as the GRO, where the research focuses on novel methods to improve adherence in a resource poor-setting, including through the use of electronic pillboxes and therapeutic drug monitoring using dried blood spots. My prior adherence work has contributed to policy in the Western Cape and nationally, as well as to international guidelines.