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Pharmacometrics as a career

Are you a talented, data skilled person with a passion for biomedical research? Then pharmacometrics could be an exciting career for you. Check out our Career page for more information and current vacancies.

What is pharmacometrics?

Pharmacometrics uses mathematical models based on biology, pharmacology, physiology, and disease to quantify the interactions between drugs and patients.

Pharmacometrics at UCT

The pharmacometrics group at UCT, led by Prof. Paolo Denti, is an international growing team with focus on antiretroviral and antituberculosis agents in neglected populations.

Our team

Cape Town

We have the privilege of calling Cape Town our home, a beautiful city nestled between the iconic Table Mountain and stunning coastlines. It offers an unrivaled blend of nature and vibrant culture and is the ultimate location for adventure!

Are you new to pharmacometrics?

If you're interested in learning more about pharmacometrics, check out Pharmacometrics Africa, an NGO that runs open access educational programs with the aim to develop quantitative clinical pharmacology among African scientists.

PMX Africa

Pharmacometrics as a career

What is pharmacometrics?

Pharmacometrics uses mathematical models based on biology, pharmacology, physiology, and disease to quantify the interactions between drugs and patients.

Pharmacometrics at UCT

The pharmacometrics group at UCT, led by Prof. Paolo Denti, is an international growing team with focus on antiretroviral and antituberculosis agents in neglected populations.

Our team

Cape Town

Are you new to pharmacometrics?

PMX Africa

Pharmacometrics as a career

New Study Provides Key Insights on Dolutegravir Use in Children Receiving Tuberculosis Treatment

Findings from the ORCHID study, and where to find them.

New study confirms safe and more effective malaria prevention for children with sickle cell anaemia

Weekly dihydroartemisinin–piperaquine offers safer and more effective malaria prevention for children with sickle cell anaemia, according to a new study in the Lancet.

Advancing Pharmacokinetics: The ISSX Africa Workshop 2025

A look back at our trip to Johannesburg for the first-ever ISSX Africa Workshop 2025.

Advancing Malaria Prevention: PDMC Consortium Trials Update in Malawi

Roeland visited Zomba, Malawi, to discuss progress on PDMC consortium trials, share CHEMCHA findings with policymakers, and refine the design of the upcoming PDMC-SAM study.

How should rifabutin be dosed in children during HIV co-treatment with lopinavir/ritonavir?

Gebreyesus et al. have characterized the interaction between rifabutin and lopinavir/ritonavir in children to optimize rifabutin dosing during co-treatment.

What is the optimal prophylactic dosing regimen for cefazolin during on-pump cardiac surgery in children?

Gebreyesus et al. have characterized the pharmacokinetics of cefazolin in children during cardiac surgery with cardiopulmonary bypass (CPB) and investigated the optimal dosing regimen for prophylaxis of surgical site infections.

We are hiring!

Check out these exciting opportunities for joining our group in Cape Town!

Does alcohol use affect tuberculosis treatment?

In our most recent publication, Wijk et al. explored the effect of alcohol consumption and illicit drug use on the pharmacokinetics of first-line tuberculosis treatment.

Lufina receives the young scientist best presentation award

Lufina was awarded the young scientist best presentation award at the 26th PK/PD expert meeting held in Isny, Germany in March 2024.

Collaboration with World Health Organization presented at CROI2024: Simplifying Dosing by Harmonizing Weight-Band-Based Dosing Across Therapeutic Areas in Children

We explored the simplification of dosing for children by harmonizing weight band-based dosing across disease areas in collaboration with the WHO and GAP-f. The results were presented by Dr. Hylke Waalewijn at the CROI2024 in Denver.