Scientific publications:  2001 to 2023. Click here. 

For a comprehensive list of publications from 2000 to present, visit out Pubmed bibliography. Click here.

 

Scientific publications:  2023 (below).

Poly(ADP)ribose polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production.

Thirunavukkarasu S, Ahmed M, Rosa BA, Boothby M, Cho SH, Rangel-Moreno J, Mbandi SK, Schreiber V, Gupta A, Zúñiga J, Mitreva M, Kaushal D, Scriba TJ, Khader SA.

Journal of Clinical Investigation, 18:e158630.. Read Publication. 

Systematic review of diagnostic and prognostic host blood transcriptomic signatures of tuberculosis disease in people living with HIV.

Mendelsohn SC, Verhage S, Mulenga H, Scriba TJ, Hatherill MGates Open Research, 5;7:27. Read Publication.

World Tuberculosis Day 2023 theme "Yes! We Can End TB!"

Goletti D, Al-Abri S, Migliori GB, Coler R, Ong CWM, Esposito SMR, Tadolini M, Matteelli A, Cirillo D, Nemes E, Zumla A, Petersen E.

 International Journal of Infectious Diseases, 7:S1201-9712(23)00137-6. Epub ahead of print.Read publication. 

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.

Swanson RV, Gupta A, Foreman TW, Lu L, Choreno-Parra JA, Mbandi SK, Rosa BA, Akter S, Das S, Ahmed M, Garcia-Hernandez ML, Singh DK, Esaulova E, Artyomov MN, Gommerman J, Mehra S, Zuniga J, Mitreva M, Scriba TJ, Rangel-Moreno J, Kaushal D, Khader SA.
Natural Immunology,. Read publication.

Clinical trials of tuberculosis vaccines in the era of increased access to preventive antibiotic treatment.

Rangaka MX, Frick M, Churchyard G, García-Basteiro AL, Hatherill M, Hanekom W, Hill PC, Hamada Y, Quaife M, Vekemans J, White RG, Cobelens F.

Lancet Respiratory Medicine, 11(4):380-390. Read publication.

NK-like CD8+ γδ T cells are expanded in persistent Mycobacterium tuberculosis infection.

Roy Chowdhury R, Valainis JR, Dubey M, von Boehmer L, Sola E, Wilhelmy J, Guo J, Kask O, Ohanyan M, Sun M, Huang H, Huang X, Nguyen PK, Scriba TJ, Davis MM, Bendall SC, Chien YH.

Science Immunology, 8(81):eade3525. Read publication.

Virome-wide detection of natural infection events and the associated antibody dynamics using longitudinal highly-multiplexed serology.

Kelley EJ, Henson SN, Rahee F, Boyle AS, Engelbrektson AL, Nelson GA, Mead HL, Anderson NL, Razavi M, Yip R, Ladner JT, Scriba TJ, Altin JA.

Nature Communications, 14(1):1783. Read publication.

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.

Swanson RV, Gupta A, Foreman TW, Lu L, Choreno-Parra JA, Mbandi SK, Rosa BA, Akter S, Das S, Ahmed M, Garcia-Hernandez ML, Singh DK, Esaulova E, Artyomov MN, Gommerman J, Mehra S, Zuniga J, Mitreva M, Scriba TJ, Rangel-Moreno J, Kaushal D, Khader SA.

Nature Immunology, epub ahead of print. Read publication.

T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection.

Musvosvi M, Huang H, Wang C, Xia Q, Rozot V, Krishnan A, Acs P, Cheruku A, Obermoser G, Leslie A, Behar SM, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Walzl G, Hatherill M, Davis MM, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium.

Nature  Medicine, 29(1):258-269. Read publication.

Utility of a three-gene transcriptomic signature in the diagnosis of tuberculosis in a low-endemic hospital setting.

Chendi BH, Jooste T, Scriba TJ, Kidd M, Mendelsohn S, Tonby K, Walzl G, Dyrhol-Riise AM, Chegou NN.

Infectious Diseases (London), 55(1):44-54. Read publication.

Factors associated with prevalent Mycobacterium tuberculosis infection and disease among adolescents and adults exposed to rifampin-resistant tuberculosis in the household.

Kim S, Hesseling AC, Wu X, Hughes MD, Shah NS, Gaikwad S, Kumarasamy N, Mitchell E, Leon M, Gonzales P, Badal-Faesen S, Lourens M, Nerette S, Shenje J, de Koker P, Nedsuwan S, Mohapi L, Chakalisa UA, Mngqbisa R, Escada RODS, Ouma S, Heckman B, Naini L, Gupta A, Swindells S, Churchyard G.

PLoS One. 2023;18(3):e0283290. Read publication.

Newborn bacille Calmette-Guérin vaccination induces robust infant interferon-γ-expressing natural killer cell responses to mycobacteria.

Murphy M, Suliman S, Briel L, Veldtsman H, Khomba N, Africa H, Steyn M, Snyders CI, van Rensburg IC, Walzl G, Chegou NN, Hatherill M, Hanekom WA, Scriba TJ, Nemes E.

International Journal of Infectious Diseases, 25:S1201-9712(23)00069-3 Read publication.

 
Standardized Approach for Collection of Objective Data to Support Outcome Determination for Late-Phase TB Trials.
Kurbatova EV, Phillips PP, Dorman SE, Sizemore EE, Bryant KE, Purfield AE, Ricaldi J, Brown NE, Johnson JL, Wallis CL, Akol JP, Ocheretina O, Van Hung N, Mayanja-Kizza H, Lourens M, Dawson R, Nhung NV, Pierre S, Musodza Y, Shenje J, Badal-Faesen S, Vilbrun SC, Waja Z, Peddareddy L, Scott NA, Yuan Y, Goldberg SV, Swindells S, Chaisson RE, Nahid P.
American Journal of Respiratory and Critical Care Medicine, Read publication.
Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis.

Hamada Y, Gupta RK, Quartagno M, Izzard A, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Huerga H, Jones-López EC, Kinikar A, Lange C, van Leth F, Liu Q, Lu W, Lu P, Rueda IL, Martinez L, Mbandi SK, Muñoz L, Padilla ES, Paradkar M, Scriba T, Sester M, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Thiruvengadam K, Vashishtha R, Abubakar I, Rangaka MX.

EClinicalMedicine, 5;56:101815. Read publication

Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile.

Chihab LY, Kuan R, Phillips EJ, Mallal SA, Rozot V, Davis MM, Scriba TJ, Sette A, Peters B, Lindestam Arlehamn CS; SATVI Study Group.

HLA.101(2):124-137. Read publication

Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis.

Hillman H, Khan N, Singhania A, Dubelko P, Soldevila F, Tippalagama R, DeSilva AD, Gunasena B, Perera J, Scriba TJ, Ontong C, Fisher M, Luabeya A, Taplitz R, Seumois G, Vijayanand P, Hedrick CC, Peters B, Bure.

Frontiers of Immunology, 13:1087010. Read publication.

T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection.
Musvosvi M, Huang H, Wang C, Xia Q, Rozot V, Krishnan A, Acs P, Cheruku A, Obermoser G, Leslie A, Behar SM, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Walzl G, Hatherill M, Davis MM, Scriba TJ.
Nature Medicine, 29(1):258-269. Read publication.
Utility of a three-gene transcriptomic signature in the diagnosis of tuberculosis in a low-endemic hospital setting.

Chendi BH, Jooste T, Scriba TJ, Kidd M, Mendelsohn S, Tonby K, Walzl G, Dyrhol-Riise AM, Chegou NN.

Infectious Diseases (Lond), 55(1):44-54, Re

ad publication.

Meeting report: 6th Global Forum on Tuberculosis Vaccines, 22–25 February 2022, Toulouse, France.

Young, C., Suliman, S., Rozot, V. and Mendelsohn, S.C.Vaccine: X13, p.100267. Read publication.