News from the South African Tuberculosis Vaccine Initiative.
Opinion piece: The hunt for a new TB vaccine: Why we are now so close, and why it matters.
A/Prof Angelique Luabeya writes in the Spotlight that the world’s only TB vaccine, BCG is over a century old and offers limited protection. South Africa researchers are leading trials of 3 new candidates, signalling a breakthrough.
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Upcoming seminar: Professors Hatherill & Nemes- TB Vaccines & Immunology Seminar, 19 March 2026 (13:00–14:00)
The South African Immunology Society will host a seminar on 19 March where Professors Mark Hatherill and Elisa Nemes will outline the latest advances in TB vaccines and immunology.
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Narrative history of the South African Tuberculosis Vaccine Initiative
A narrative history of the South African Tuberculosis Vaccine Initiative as told through the voices of the many people who were involved in setting up and sustaining the organisation from 2001 to the present.
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New modelling study shows impact of late stage TB vaccines depends on their ability to prevent infectious, asymptomatic TB
New research, co-authored by SATVI’s Professor Mark Hatherill, has found that the real-world impact of late-stage tuberculosis (TB) vaccines may depend heavily on how well they protect against infectious, asymptomatic TB.
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Vacancies
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Previous highlights
Professor Mark Hatherill addresses United Nations High-level Meeting on Tuberculosis
SEPTEMBER 2023: Prof Mark Hatherill, addressed the UN High-level Meeting on Tuberculosis, calling for a quantum jump in TB vaccine research and development (R&D) funding, to deliver the transformative tools needed to end the TB pandemic.
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Phase 1b/2a clinical trial in adults of novel TB vaccine candidate MTBVAC shows promising results.
Findings from the IAVI A-050 study, published in Lancet Global Health, demonstrate that vaccination with MTBVAC caused similar or stronger immune responses compared to the BCG vaccine in adults, of MTBVAC were as safe as BCG.
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