Academic Appointments
- Sam Nightingale is an Associate Professor of Neurology at the University of Cape Town.
Research Interests
My research focuses on cognitive impairment and the neurology of HIV infection. I am co-PI of the CONNECT study, investigating the CNS effects of the programmatic shift from efavirenz- to dolutegravir-based antiretroviral therapy in Cape Town. I am PI of the Ingqondo study, funded by the Donald Gordon Foundation and Race Against Dementia, which examines inflammatory and infective mechanisms of Alzheimer’s disease. I chair the International HIV-Cognition Working Group, reframing criteria for cognitive impairment in people living with HIV.
Research Areas
Clinical Neuroscience • Cognitive & Behavioural Neuroscience
Contact Details
Selected Publications
Nightingale S, Ances B, Cinque P, Dravid A, Dreyer AJ, Gisslén M, Joska JA, Kwasa J, Meyer AC, Mpongo N, Nakasujja N, Pebody R, Pozniak A, Price RW, Sandford C, Saylor D, Thomas KGF, Underwood J, Vera JH, Winston A. Cognitive impairment in people with HIV: consensus recommendations for a new approach. Nature Reviews Neurology. June 2023.
Nightingale S, Cinque P, Joska JA, Price RW, Underwood J, on behalf of the International HIV-Cognition Working Group. A new approach to cognitive impairment in people with HIV. The Lancet HIV. Sept 2022
Nightingale S, Dreyer AJ, Saylor D, Gisslén M, Winston A, Joska JA. Moving on From HAND: Why We Need New Criteria for Cognitive Impairment in Persons Living With Human Immunodeficiency Virus and a Proposed Way Forward. Clinical Infectious Diseases. Sept 2021