(IPD) data meta-analyses

As a founding member of the WorldWide Antimalarial Resistance Network (WWARN), the malaria theme within the Infectious Diseases Data Observatory (IDDO), we conduct individual patient data (IPD) data meta-analyses, a method WWARN has pioneered to increase statistical power, enabling key research questions to be answered that individual studies are unlikely to resolve. These meta-analyses underpin the WWARN collaborative platform, generating innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines.

WWARN Clinical Trials Toolkit

In addition, we manage the WWARN Clinical Trials Toolkit, a pathway with a step by step guide for researchers on how to plan, design, execute and interpret malaria clinical trial results, collecting reliable and comprehensive evidence in a standardised format.

CDISC Malaria Therapeutic User Guide

An important component is the CDISC Malaria Therapeutic User Guide and CDASH compliant CRF, led by CCOAT, that facilitates alignment of electronic acquisition, exchange, submission and archiving of clinical malaria data collection, a requirement by the UD FDA and other medicines authorities