Lufina Tsirizani Galileya

Postdoctoral Research Fellow

Lufina is a post-doctoral fellow in pharmacometrics.

Lufina joined us for her PhD studies in October 2019 and went on as a post-doctoral fellow in February 2025. She is working on the application of nonlinear mixed-effects models to describe pharmacokinetics (PK) and pharmacodynamics (PD) of antimalarial and antituberculotic and drugs in children. She holds a Bachelor of Pharmacy(Hons.) and a MSc Epidemiology with specialisation in Epidemiology and Biostatistics from the University of Malawi, College of Medicine. Her interest in drug development led Lufina to study pharmacy, which then sparked her strong interest in PK and PD. Specifically, Lufina is interested in the application of PK and PD in drug dose optimization and drug development for vulnerable populations. Before taking up the PhD position Lufina was a research pharmacist on phase III clinical trials in Malawi.

Research projects

Lufina is part of the research team on the following studies:

Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the
Chemoprevention of Malaria in Children with Sickle Cell Anaemia in eastern and southern Africa: a double-blind placebo controlled randomised trial (the CHEMCHA trial)
SHINE study: Shorter treatment for minimal TB in children. ISRCTN63579542

Research interests

Application of pharmacometric modelling and simulation tools in drug development and drug dose optimization for children and other vulnerable populations.

Software: NONMEM, Monolix, R, STATA.