Flyer for COIN Unit solvathon
The Clinical Omics and Informatics (COIN) Unit invites applications for participation in our upcoming Rare Disease Solvathon- a collaborative two day event on 20 and 21 November 2026 focused on solving rare and undiagnosed disease cases using high-fidelity (HiFi) long-read whole genome sequencing. We have secured sponsorship from PacBio and Inqaba Biotec to sequence 16 genomes using PacBio's HiFi technology for selected high-priority cases. Participants will be allocated to multidisciplinary teams to work on real rare disease cases submitted by Solvathon participants, analysing genomic and clinical data in real time to identify potential genetic diagnoses using the LucidGenomics software platform. This event is open to clinicians, researchers, medical scientists, students, bioinformaticians, genetic counsellors and anyone with an interest in diagnosing rare diseases. Please note:
  • The Solvathon is an in-person event and no online participation will be offered
  • Case submitters must be available to attend and actively participate in the event
  • Case submissions across all disease areas are welcome
  • All selected cases must have appropriate consent and meet the necessary ethical and sample eligibility criteria
  • The event will also include a dedicated teaching component, introducing participants to HiFi long-read sequencing technology and the analytical tools used to work with and interpret this type of data.

You may apply as:

  • A case submitter and participant
  • A participant (no case submission)