Prof Meintjes is a Professor of Medicine at the University of Cape Town (UCT) and Clinical Professor of Infectious Diseases at Queen Mary University of London (QMUL). He is an adult Infectious Diseases physician and clinician scientist. He leads a research programme that focuses on the clinical conditions affecting patients with advanced HIV disease including disseminated HIV-associated tuberculosis, the immune reconstitution inflammatory syndrome and cryptococcal meningitis. His group also investigates drug-resistant tuberculosis, diagnostics for TB and antiretroviral therapy strategies. He has been the PI or local PI of several clinical trials and conducts observational cohort studies that address questions related to disease pathogenesis.

Prof Meintjes is a proud member of the RCS Gugs Athletics Club, where he finds inspiration and support from a vibrant community of fellow athletes. He has taken on some of South Africa's most challenging races, including the iconic Comrades Marathon and the scenic yet challenging Cape Town Two Oceans Marathon. With a deep passion for running, he continues to push limits, embodying the spirit of resilience and endurance both on and off the track.