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- Abdelgawad N, Wasserman S, Gausi K, Davis A, Stek C, Wiesner L, Meintjes G, Wilkinson RJ, Denti P. Population Pharmacokinetics of Rifampicin in Plasma and Cerebrospinal Fluid in Adults With Tuberculosis Meningitis. J Infect Dis. 2025 Aug 14;232(2):e234-e241. doi: 10.1093/infdis/jiaf178. PMID: 40295169.
- Calderin JM, Wasserman S, Resendiz-Galvan JE, Abdelgawad N, Davis A, Stek C, Wiesner L, Wilkinson RJ, Denti P. Population pharmacokinetics of pyrazinamide and isoniazid in plasma and cerebrospinal fluid from South African adults with tuberculous meningitis. Antimicrob Agents Chemother. 2025 Aug 6;69(8):e0009925. doi: 10.1128/aac.00099-25. Epub 2025 Jul 1. PMID: 40590723.
- De Nicolò A, Palermiti A, Mugerwa H, Nakabuye S, Namusanje J, Kobusingye J, Odoch D, Lamorde M, Kengo A, Denti P, Gausi K, Maartens G, McIlleron H, Wiesner L, Khoo S, Waitt C, D'Avolio A. Intracellular Penetration of Atazanavir, Ritonavir and Dolutegravir With Concomitant Rifampicin: A Dose Escalation Study. Clin Pharmacol Ther. 2025 May;117(5):1393-1402. doi: 10.1002/cpt.3572. Epub 2025 Jan 31. PMID: 39891354.
- Dufault SM, Davies GR, Svensson EM, Sloan DJ, McCallum AD, Patel A, Van Brantegem P, Denti P, Phillips PPJ. Analysis of time-to-positivity data in tuberculosis treatment studies: Identifying a new limit of quantification. Int J Antimicrob Agents. 2025 Feb;65(2):107404. doi: 10.1016/j.ijantimicag.2024.107404. Epub 2024 Dec 7. PMID: 39653087.
- Holovchak A, McIlleron H, Denti P, Schomaker M. Recoverability of causal effects under presence of missing data: a longitudinal case study. Biostatistics. 2025 Dec 31;26(1):kxae044. doi: 10.1093/biostatistics/kxae044. PMID: 39552060.
- Idro R, Nkosi-Gondwe T, Opoka R, Ssenkusu JM, Dennis K, Tsirizani L, Akun P, Rujumba J, Nambatya W, Kamya C, Phiri N, Joanita K, Komata R, Innussa M, Tenywa E, John CC, Tarning J, Denti P, Wasmann RE, Ter Kuile FO, Robberstad B, Phiri KS. Weekly dihydroartemisinin-piperaquine versus monthly sulfadoxine-pyrimethamine for malaria chemoprevention in children with sickle cell anaemia in Uganda and Malawi (CHEMCHA): a randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 2025 Jun;25(6):643-655. doi: 10.1016/S1473-3099(24)00737-0. Epub 2024 Dec 20. PMID: 39718172.
- Kamphuis AEM, Waalewijn H, Wasmann RE, Bamford A, Szubert A, Chabala C, Bwakura-Dangarembizi M, Makumbi S, Nangiya J, Mumbiro V, Mulenga V, Musiime V, De Wildt SN, Colbers A, Gibb DM, Burger D; AND THE CHAPAS-4 TRIAL TEAM. Pharmacokinetic data of atazanavir/ritonavir in second-line treatment of children living with HIV. J Acquir Immune Defic Syndr. 2025 Jun 16. doi: 10.1097/QAI.0000000000003704. Online ahead of print. PMID: 40521667.
- Kenfack Teponnou GA, Joubert A, Spaltman S, Merwe MV, Zangenberg E, Sawe S, Denti P, Castel S, Conradie F, Court R, Maartens G, Wiesner L. Development and validation of an LC-MS/MS multiplex assay for the quantification of bedaquiline, n-desmethyl bedaquiline, linezolid, levofloxacin, and clofazimine in dried blood spots. J Chromatogr B Analyt Technol Biomed Life Sci. 2025 Feb 1;1252:124470. doi: 10.1016/j.jchromb.2025.124470. Epub 2025 Jan 16. PMID: 39827625.
- Kengo A, Resendiz-Galvan JE, Najjemba L, Mugerwa H, De Nicolò A, D'Avolio A, Atoyebi S, Wiesner L, Svensson EM, Waitt C, Denti P. Model-based evaluation of the interaction between ritonavir-boosted atazanavir and rifampicin in Ugandan adults with HIV. Br J Clin Pharmacol. 2025 Dec;91(12):3471-3481. doi: 10.1002/bcp.70195. Epub 2025 Aug 12. PMID: 40796001.
- Naidoo A, Waalewijn H, Naidoo K, Letsoalo M, Cromhout G, Sewnarain L, Mosia NR, Osuala EC, Wiesner L, Wasmann RE, Denti P, Dooley KE, Archary M; ORCHID study team. Pharmacokinetics and safety of dolutegravir in children receiving rifampicin tuberculosis treatment in South Africa (ORCHID): a prospective cohort study. Lancet HIV. 2025 Apr;12(4):e273-e282. doi: 10.1016/S2352-3018(24)00312-6. Epub 2025 Feb 26. PMID: 40023169.
- Ndzamba B, Denti P, McIlleron H, Smith P, Mthiyane T, Rustomjee R, Onyebujoh P, Reséndiz-Galván JE. Pharmacokinetics of ethambutol and weight banded dosing in South African adults newly diagnosed with tuberculosis and HIV. Antimicrob Agents Chemother. 2025 Feb 13;69(2):e0120024. doi: 10.1128/aac.01200-24. Epub 2024 Dec 23. PMID: 39714183.
- Palmer M, Zou Y, Hesseling AC, van der Laan L, Courtney I, Kinikar AA, Sonkawade N, Paradkar M, Kulkarni V, Casalme DJO, Frias MVG, Draper H, Wiesner L, Karlsson MO, Denti P, Svensson EM, Garcia-Prats AJ. Population pharmacokinetics and dosing of dispersible moxifloxacin formulation in children with rifampicin-resistant tuberculosis. Br J Clin Pharmacol. 2025 Jun;91(6):1853-1864. doi: 10.1111/bcp.70005. PMID: 40441696.
- Pillai GC, Mouksassi S, Asiimwe IG, Rayner CR, Kern S, Sinxadi P, Denti P, Decloedt E, Waitt C, Ogutu BR, de Greef R. Advancing pharmacometrics in Africa-Transition from capacity development toward job creation. CPT Pharmacometrics Syst Pharmacol. 2025 Mar;14(3):407-419. doi: 10.1002/psp4.13291. Epub 2024 Dec 9. PMID: 39648964.
- Resendiz-Galvan JE, Arora PR, Lokhande RV, Udwadia ZF, Rodrigues C, Gupta A, Tornheim JA, Denti P, Ashavaid TF; The MDR-TB MUKT and Indo-South Africa Study Teams; MDR-TB MUKT and Indo-South Africa Study Teams. Evaluation of cycloserine dose regimens in an Indian cohort with multidrug-resistant tuberculosis: a population pharmacokinetic analysis. Antimicrob Agents Chemother. 2025 Oct;69(10):e0010125. doi: 10.1128/aac.00101-25. Epub 2025 Sep 2. PMID: 40891988.
- Sawe S, Tsirizani L, Mkhize B, Wiesner L, Maartens G, Conradie F, Court R, Loveday M, Waitt C, Denti P. Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin-resistant tuberculosis. Br J Clin Pharmacol. 2025 Dec 2. doi: 10.1002/bcp.70386. Online ahead of print. PMID: 41330388.
- Sawe S, Tsirizani L, Court R, Gausi K, Poswa A, Badat T, Wiesner L, Loveday M, Maartens G, Conradie F, Denti P. The effect of pregnancy on the population pharmacokinetics of levofloxacin in South Africans with rifampicin-resistant tuberculosis. Antimicrob Agents Chemother. 2025 May 7;69(5):e0162624. doi: 10.1128/aac.01626-24. Epub 2025 Apr 1. PMID: 40167446.
- Tsirizani L, Waalewijn H, Szubert A, Mulenga V, Chabala C, Bwakura-Dangarembizi M, Chitsamatanga M, Rutebarika DA, Musiime V, Kasozi M, Lugemwa A, McIlleron HM, Burger DM, Gibb DM, Colbers A, Denti P, Wasmann RE; CHAPAS-4 trial team. Population pharmacokinetics of ritonavir as a booster of lopinavir, atazanavir, or darunavir in African children with HIV. Antimicrob Agents Chemother. 2025 Nov 5;69(11):e0077125. doi: 10.1128/aac.00771-25. Epub 2025 Sep 26. PMID: 41004270.
- Upton CM, Calderin JM, Diacon AH, Boeree MJ, Denti P, Wiesner L, Kellermann T, McCulloch M, Aarnoutse R. Cerebrospinal fluid penetration of cycloserine/terizidone and clofazimine in patients with pulmonary TB. Antimicrob Agents Chemother. 2025 Dec 10;69(12):e0093125. doi: 10.1128/aac.00931-25. Epub 2025 Oct 21. PMID: 41118340.
- Waalewijn H, Almett M, Wasmann RE, Cressey TR, Easterbrook P, Olumese PE, Hesseling AC, Garcia-Prats AJ, Tarning J, Turkova A, Viney K, Svensson EM, Colbers A, Were WM, Denti P, Penazzato M; members of the expert panels. Simplifying medicine dosing for children by harmonising weight bands across therapeutic areas. Lancet Child Adolesc Health. 2025 Apr;9(4):274-282. doi: 10.1016/S2352-4642(25)00025-2. PMID: 40113369.
- Wijk M, Denti P, Gausi K, Myers B, Carney T, White LF, Theron D, Parry CDH, Horsburgh CR, Rawoot N, Warren RM, Court R, Kulkarni SG, Farhat MR, Buys C, Malatesta S, Weber SE, Kulkarni S, McIlleron H, Jacobson KR, Kloprogge F. Insights into the Role of Rifampicin Exposure and Clinical Baseline Covariates on the Response to Pulmonary Tuberculosis Treatment. Clin Infect Dis. 2025 Oct 24:ciaf586. doi: 10.1093/cid/ciaf586. Online ahead of print. PMID: 41133922.
- Wijk M, Wasmann RE, Jacobson KR, Svensson EM, Denti P. A Pragmatic Approach to Handling Censored Data Below the Lower Limit of Quantification in Pharmacokinetic Modeling. CPT Pharmacometrics Syst Pharmacol. 2025 Jun;14(6):1042-1049. doi: 10.1002/psp4.70015. Epub 2025 Mar 11. PMID: 40067154.