Professor Thomas Scriba

Deputy Director: SATVI

Professor Scriba is an immunologist and heads a team of clinical immunologists, post-doctoral fellows and postgraduate students at UCT where he is a Member of the Institute of Infectious Disease and Molecular Medicine; he is also Deputy Director (Immunology) at the South African Tuberculosis Vaccine Initiative (SATVI). SATVI’s mission is the development of new and effective prevention strategies against TB, including vaccination and biomarker-targeted treatment approaches. His particular interests focus on immunopathology of mycobacterial infection and TB disease, correlates of risk of M. tuberculosis infection and TB disease, immunological development in childhood, and novel TB vaccine development. He has been co-investigator on more than 15 phase I/II/IIb clinical trials of novel TB vaccines, and has led the design and immunological analyses of vaccine-induced T cell responses for most of these. In the last 5 years he has also been leading studies of correlates of risk of TB in different cohorts.
 
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