Noha Abdelgawad

Noha is a PhD Student and joined the Pharmacometrics Group in October 2019.

She holds a master’s degree in Pharmaceutics and a bachelor’s degree in Pharmaceutical Sciences from the Faculty of Pharmacy, Helwan University in Egypt. After graduating, she worked as a pharmacokineticist in bioequivalence centres for six years. 

Her research focuses on tuberculosis (TB) and the use of nonlinear mixed-effects modelling to describe the PK/PD of drugs used in TB patients.

Research projects

Noha is currently involved in several different projects including: 

• PopPK modelling of rifampicin and linezolid in plasma and cerebrospinal fluid (CSF) in adults with tuberculosis meningitis (TBM)
• PopPK modelling of rifampicin in plasma, CSF, and brain extracellular fluid in children with TBM
• PopPK modelling of rifampicin, isoniazid, and pyrazinamide in hospitalised TB patients versus outpatients
• Pharmacometric approaches to adherence assessment 
• Simulations to inform weight-based dosing of first-line anti-TB drugs
• PopPK modelling of anti-TB drugs in central nervous system tissues from a preclinical rabbit TBM model

Research interests

• Nonlinear mixed-effects modelling to develop PK/PD models
• Statistical analysis using R
• Optimal designs
• Bioequivalence