What is pharmacometrics?
Pharmacometrics uses mathematical models based on biology, pharmacology, physiology, and disease to quantify the interactions between drugs and patients.
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Pharmacometrics at UCT
The pharmacometrics group at UCT, led by Prof. Paolo Denti, is an international growing team with focus on antiretroviral and antituberculosis agents in neglected populations.
Our team
Cape Town
We have the privilege of calling Cape Town our home, a beautiful city nestled between the iconic Table Mountain and stunning coastlines. It offers an unrivaled blend of nature and vibrant culture and is the ultimate location for adventure!
Are you new to pharmacometrics?
If you're interested in learning more about pharmacometrics, check out Pharmacometrics Africa, an NGO that runs open access educational programs with the aim to develop quantitative clinical pharmacology among African scientists.
PMX Africa
Pharmacometrics as a career
Are you a talented, data skilled person with a passion for biomedical research? Then pharmacometrics could be an exciting career for you. Check out our Career page for more information and current vacancies.
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Could metformin affect the drugs used to treat tuberculosis?
Our newly published study found that metformin lowered exposure to rifampicin and isoniazid. Model-based simulations suggest a small increase in rifampicin dose could help overcome this interaction.
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Newly published study on atazanavir/r use in African children with HIV
More children with HIV are living long enough to need a subsequent-line drug. Our study explores how to dose it safely - and potentially alongside TB treatment.
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Personalised Adherence Monitoring: Pharmacometrics Applied to TB Prevention
Can pharmacokinetic modelling improve TB treatment adherence monitoring? Our latest study applies pharmacometrics to the REMEMBER clinical trial to establish personalised drug concentration thresholds.
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Applications Open: PhM-2026 Online Pharmacometrics Course
Sign up for a 12-week online pharmacometrics course - at no charge!
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