PUBLICATIONS
(past five years)

2024:

  1. Simmonds WM, Awuku Y, Barrett C, Brand M, Davidson K, Epstein D, et al. [Louw VJ 12th author]. Guidance for the gastrointestinal evaluation and management of iron deficiency in Sub-Saharan Africa. S Afr Med J. 2024 Feb. ;114(1b):e711. https://samajournals.co.za/index.php/samj/article/view/711
  2. Takalani A, Robinson M, Jonas P,  Bodenstein A, Sambo V, et al. [Louw V 7th author and Opie J 8th author]. Safety of a second homologous Ad26.COV2.S vaccine among healthcare workers in the phase 3b implementation Sisonke study in South Africa, Vaccine, Volume 42, Issue 6, 2024, Pages 1195-1199, ISSN 0264-410X,  https://doi.org/10.1016/j.vaccine.2024.01.066
  3. Opie J, Verburgh E, Bailly J, Mayne E, Louw V, Hematological Complications of HIV Infection: An Update from an HIV-endemic setting, Open Forum Infectious Diseases, 2024, ofae162, https://doi.org/10.1093/ofid/ofae162
  4. Davison, Glenda Mary and Jessica, Opie and Davids, Saarah FG and Mohamed, Rygana and Novitzky, Nicolas, Early Recovery of Natural Killer Cells Post T-Cell Depleted Allogeneic Stem Cell Transplantation Using Alemtuzumab 'In the Bag'. Available at SSRN: https://ssrn.com/abstract=4300095

2023:

  1. Nell EM, Bailly J, Oelofse D, Linstrom M, Opie J, Chapanduka ZC, et al. Multicentre verification of haematology laboratory blood collection tubes during a global blood collection tube shortage. Int J Lab Hematol. 2023. https://doi.org/10.1111/ijlh.14129 
  1. Jenkins N, Blanshard LA, Stone M, Verburgh E, Oosthuizen J, Shires K. Cytogenetically Normal Acute Myeloid Leukaemia at a Single Centre in South Africa. Hematol Oncol Stem Cell Ther. 2023 May 23;16(4):397-406. https://doi.org/10.56875/2589-0646.1087
  1. De John KO, De Quintal H, Mathibe MD, Albertus N, Opie JJ. A rare case of acute megakaryoblastic leukaemia with constitutional ring chromosome 21. Br J Haematol. 2023 Jun 6. https://doi.org/10.1111/bjh.18892
  1. Mandal S, Smith DL, Peter PJ, Louw VJ, Sil S, Ibrahim IN, Maji M, Nath S. Perioperative Anemia Management. Annals of Blood. Published online: 26 June 2023. doi: 10.21037/aob-22-42. https://dx.doi.org/10.21037/aob-22-42
  1. Jagga WM, Biccard B, Bailly J, Esmail A, Antel K, Opie J. Point of care ultrasound findings in critically ill SARS-COV2 patients in an HIV endemic, resourced constrained setting.  Heliyon, Volume 9, Issue 6, June 2023, https://doi.org/10.1016/j.heliyon.2023.e16519
  1. Van Staden Q, Bailly J, Louw VJ. T-Cell Large Granular Lymphocytic Leukaemia in a South African Patient Living with HIV. IJCMCR. 2023 May 2; 26(1):1-4. https://ijclinmedcasereports.com/pdf/IJCMCR-CR-00629.pdf
  1. Shires K, Rust A, Harryparsad R, Coburn J, Gopie, R. JAK2/STAT5 Pathway Mutation Frequencies in South African BCR/ABL Negative MPN Patients. Hematol Oncol Stem Cell Ther. 2023 Apr 4 https://doi.org/10.56875/2589-0646.1064
  1. Jacobson BF, Schapkaitz E, Takalani A, Rowji PF, Louw V, Opie J, Bekker LG et al. Vascular thrombosis after single dose Ad26.COV2.S vaccine in healthcare workers in South Africa: open label, single arm, phase 3B study (Sisonke study). BMJ Med. 2023 Mar 23.  http://dx.doi.org/10.1136/bmjmed-2022-000302
  1. Antel K, Oosthuizen J, Brown K, Malherbe F, Loebenberg P, Seaton C, Baloyi S, Simba K, Chetty D, Louw VJ, Maartens G, Verburgh ER. Focused investigations to expedite cancer diagnosis among patients with lymphadenopathy in a tuberculosis and HIV-endemic region. AIDS. 2023 Mar 15;37(4):587-594. https://pubmed.ncbi.nlm.nih.gov/36472201/
  1. Simba K, Mohamed Z, Opie JJ, Andera LF, Brown K, Oosthuizen J, Antel K, Dawood T, Van der Vyfer L, Du Toit C, Louw VJ, Verburgh E. The International Prognostic Score and HIV status predict red cell concentrate transfusion needs in Hodgkin lymphoma. Leuk Lymphoma. 2023 Mar;64(3):613-620. http://dx.doi.org/10.1080/10428194.2022.2157214
  1. van den Berg K, Murphy EL, Louw VJ, Maartens G, Hughes SD. Motivations for blood donation by HIV-positive individuals on antiretrovirals in South Africa: A qualitative study. Transfus Med. 2023 Feb 17. https://doi.org/10.1111/tme.12957
  1. Arora S, Goel R, Al-Riyami AZ, Al-Rawas AH, Al Hosni S, Montanari M et al. [Louw V 38th author]. International Forum on Small-Volume Transfusions in Neonates and Paediatric Patients: Summary. Vox Sang. 2023 Mar;118(3):223-229. https://doi.org/10.1111/vox.13399
  1. Arora S, Goel R, Al-Riyami AZ, Al-Rawas AH, Al Hosni S, Montanari M et al. [Louw V 38th author]. International Forum on Small-Volume Transfusions in Neonates and Paediatric Patients: Responses. Vox Sang. 2023 Mar;118(3):230-251. https://doi.org/10.1111/vox.13398
  2. Louw VJ, Fraser I, Giraldo P. Management goals of type 1 Gaucher disease in South Africa: An expert Delphi consensus document on good clinical practice. PLoS One. 2023 Aug22;18(8):e0290401.   https://doi.org/10.1371/journal.pone.0290401
  3. Louw VJ, Al-Riyami AZ, Barrett CL, Johnson ST. Integrated Approach to Transfusion Education for Clinicians, Nurses, and Laboratory Professionals. In: Global Perspectives and Practices in Transfusion Medicine. 1st Edition. 2022 Editors: EichbaumQ, Abdella Y, Amar S, Barnes L, Bloch E,Delaney M, Ipe T, Smit Sibinga CT, Zacharias PJK.
  4. Sibinga CTS, Rambiritch V, Louw VJ. Transfusion Medicine Education: A Global Model Focused on Professionalism. In: Global Perspectives and Practices in Transfusion Medicine. 1st Edition. 2022 Editors: Eichbaum Q, Abdella Y, Amar S, Barnes L, Bloch E, Delaney M, Ipe T, Smit Sibinga CT, Zacharias PJK.

2022:

  1. Peter J, Day C, Takuva S, Takalani A, Engelbrecht I, Garrett N, et al.  [ Louw V 8th author and Opie J 9th author].  Allergic reactions to the Ad26.COV2.S vaccine in South Africa.  J Allergy Clin Immunol Global 2022.  https://doi.org/10.1016/j.jacig.2021.12.002
  2. Bekker LG, Garrett N, Goga A, Fairall L, Reddy, Yende-Zuma N, et al.  [Opie J 34th author and V Louw 35th author].  Effectiveness of the Ad26.COV2.S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study. Lancet. 2022. https://doi.org/10.1016/S0140-6736(22)00007-1
  3. Takuva S, Takalani A, Soecharan I, Yende-Zuma N, Reddy T, Engelbrecht I, et al. [Opie J 13th author].  Safety evaluation of the single-dose Ad26.COV2. S vaccine among healthcare workers in the Sisonke study in South Africa: A phase 3b implementation trial. PLoS Med. 2022 Jun 21.  https://doi.org/10.1371/journal.pmed.1004024
  4. Kriel M, Opie J, Louw V, Musekwa E, Brett S, Zelaya C.  Clover leaf nuclear morphology in chronic lymphocytic leukaemia with typical immunophenotype and absence of trisomy 12. Br J Haematol. https://doi.org/10.1111/bjh.18186
  5. Bailly J, Jenkins N, Chetty D, Mohamed Z, Verburgh ER, Opie J.  Plasmablastic lymphoma: An update. Int J Lab Hematol. 2022 Sept.  https://doi.org/10.1111/ijlh.13863
  6. du Toit J, Goeijenbier M, du Toit C, de Witt P, Koornhof H, Oosthuizen J, Louw VJ, Seftel M, Verburgh E. Predictors of poor haematopoietic stem cell mobilisation in patients with haematological malignancies at a South African centre. Transfus Apher Sci. 2022 Aug;61(4):103419. https://doi.org/10.1016/j.transci.2022.103419
  7. Mahlangu J, Bassa F, Bassingthwaighte M, Cruickshank AL, Du Plessis J, Goga Y, Joubert J, Louw V et al. Prophylaxis is the new standard of care in patients with haemophilia. S Afr Med J. 2022 May 31;112(6):405-408. http://www.samj.org.za/index.php/samj/article/view/13589
  8. Shaw B, Wood E, McQuilten Z, Callum J, Romon I, Sanroma P et al. [Louw VJ 23rd author]. International Forum on Home-Based Blood Transfusion: Summary. Vox Sang. 2022 Apr;117(4):616-623. https://doi.org/10.1111/vox.13200
  9. Al-Riyami AZ, Burnouf T, Wood EM, Devine DV, Oreh A, Apelseth TO et al. [Louw V 11th author]. ISBT COVID-19 Convalescent Plasma Working Group. International Society of Blood Transfusion survey of experiences of blood banks and transfusion services during the COVID-19 pandemic. Vox Sang. 2022 Jun;117(6):822-830. https://doi.org/10.1111/vox.13256
  10. van den Berg K, Glatt TN, Vermeulen M, Little F, Swanevelder R, Barrett C et al. [Louw VJ 29th author]. Convalescent plasma in the treatment of moderate to severe COVID-19 pneumonia: a randomized controlled trial (PROTECT-Patient Trial). Sci Rep. 2022 Feb 15;12(1):2552. https://www.nature.com/articles/s41598-022-06221-8
  11. Adadey SM, Wonkam-Tingang E, Alves de Souza Rios L, Aboagye ET, Esoh K, Manyisa N, De Kock C, Awandare GA, Mowla S, Wonkam A (2022). Cell-based analysis of CLIC5A and SLC12A2 variants associated with hearing impairment in two African families. Frontiers in Genetics. https://doi.org/10.3389/fgene.2022.924904
  12. Mowla S and R Ahmed (2022) HIV infection and the risk of cancer – tumorigenicity of HIV-1 auxiliary proteins. Future Virology. https://doi.org/10.2217/fvl-2022-0065

2021:

  1. du Toit JR, Mcdonald A, Brittain D, Cass M, Thomson J, Oosthuizen J, du Toit C, Seftel M, Louw VJ, Verburgh E. Is Haploidentical Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide Feasible in Sub-Saharan Africa? Transplant Cell Ther. 2021 Dec;27(12):1002.e1-1002.e8. https://doi.org/10.1016/j.jtct.2021.08.018
  1. SM Adadey, I Schrauwen, ET Aboagye, T Bharadwaj, KK Esoh, et al [S Mowla 11th author].  Further confirmation of the association of SLC12A2 with non-syndromic autosomal-dominant hearing impairment. J Hum Genet. 2021 Dec. https://doi.org/10.1038/s10038-021-00954-6
  1. Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kumaş LT, Sağdur L et al. [Louw V 67th author]. ISBT Convalescent Plasma Group. International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary. Vox Sang. 2021 Nov;116(10):1117-1135. https://doi.org/10.1111/vox.13113
  1. Manyisa N, Schrauwen I, de Souza Rios LA, Mowla S, Tekendo-Ngongang C, Popel K et al.  A Monoallelic Variant in REST Is Associated with Non-Syndromic Autosomal Dominant Hearing Impairment in a South African Family. Genes (Basel). 2021 Nov 6. https://doi.org/10.3390/genes12111765
  1. C Neethling, G Calligaro, M Miller and JJS Opie.  The evolution of clot strength in critically-ill COVID-19 patients: a prospective observational thromboelastography study. Thromb J. 2021 Nov 6. 
    https://doi.org/10.1186/s12959-021-00331-5
  1. A de Koker, AR Bird, C Swart, JJ Rogerson, C Hilton, JJ Opie.  Establishing local reference intervals for full blood count and white blood cell differential counts in Cape Town, South Africa. S Afr Med J. https://doi.org/10.7196/SAMJ.2021.v111i4.15313
  1. Shaw B, Wood E, McQuilten Z, Callum J, Romon I, Sanroma P et al. [Louw V 22nd author]. International Forum on Home-Based Blood Transfusion: Responses. Vox Sang. 2021 Oct 25. https://doi.org/10.1111/vox.13199
  1. Shaw B, Wood E, McQuilten Z, Callum J, Romon I, Sanroma P et al. [Louw V 22nd author].  International Forum on Home-Based Blood Transfusion: Summary. Vox Sang. 2021 Oct 25. https://doi.org/10.1111/vox.13200 
  1. Smit Sibinga CT, Louw VJ, Nedelcu E, Al-Riyami AZ, Bakhtary S, Johnson ST et al; Subcommittee on Education of the AABB Global Transfusion Forum. Modeling global transfusion medicine education. Transfusion. 2021 Oct;61(10):3040-3049. https://doi.org/10.1111/trf.16641
  1. A de Koker, C Swart, J Rogerson, C Hilton, A Bird, J Opie.  Full blood count reference intervals in the healthy population residing in the Cape Town region, South Africa. Int J Lab Hematol. https://doi.org/10.1111/ijlh.13430
  1. K Shires, T Van Wyk, K Wienand.  The expression of multiple cancer/testis antigens can potentially be used to detect circulating disease and clonal evolution in the peripheral blood of multiple myeloma patients. Blood Res. 2021 Sep 30. https://doi.org/10.5045/br.2021.2020335
  1. S Takuva, A Takalani, N Garrett, A Goga, J Peter, V Louw, J Opie, et al.  Thromboembolic Events in the South African Ad26.COV2.S Vaccine Study. N Engl J Med. 2021 Aug 5.http://dx.doi.org/10.1136/bmjmed-2022-000302
  1. BR Ramorola, T Goolam-Hoosen, L Alves de Souza Rios, S Mowla.  Modulation of Cellular MicroRNA by HIV-1 in Burkitt Lymphoma Cells-A Pathway to Promoting Oncogenesis. Genes (Basel). 2021 Aug 24.http://dx.doi.org/10.1136/bmjmed-2022-000302
  1. Rambiritch V, Verburgh E, Louw VJ. Patient blood management and blood conservation - Complimentary concepts and solutions for blood establishments and clinical services in South Africa and beyond. Transfus Apher Sci. 2021 Aug;60(4):103207. https://doi.org/10.1016/j.transci.2021.103207
  1. van den Berg K, Vermeulen M, Louw VJ, Murphy EL, Maartens G. Undisclosed HIV status and antiretroviral therapy use among South African blood donors. Transfusion. 2021 Aug;61(8):2392-2400. https://doi.org/10.1111/trf.16571
  1. Bailly J, Haupt L, Joubert J, Loebenberg P, Jacobson BF, Louw VJ, Wessels PF, Opie JJ. Heparin-induced thrombocytopenia: An update for the COVID-19 era. S Afr Med J. 2021 Jul 20;111(9):841-848. http://dx.doi.org/10.7196/SAMJ.2021.v111i9.15909 
  1. Hofmann A, Spahn DR, Holtorf AP; PBM Implementation Group. Making patient blood management the new norm(al) as experienced by implementors in diverse countries. BMC Health Serv Res. 2021 Jul 2;21(1):634. https://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-021-06484-3
  1. L Alves de Souza Rios, L Mapekula, N Mdletshe, D Chetty, S Mowla.  HIV-1 Transactivator of Transcription (Tat) Co-operates With AP-1 Factors to Enhance c-MYC Transcription. Front Cell Dev Biol. 2021 Jun 30. https://doi.org/10.3389/fcell.2021.693706
  1. Shein R, Mashigo N, du Toit CE, Oosthuizen J, Seftel MD, Louw VJ, Verburgh E. Outcomes for Patients With Acute Promyelocytic Leukemia in South Africa. Clin Lymphoma Myeloma Leuk. 2021 Apr;21(4):e348-e352. https://doi.org/10.1016/j.clml.2020.12.006
  1. Seftel MD, Louw V. A century between pandemics and poisonings. Lancet Haematol. 2021 Apr;8(4):e251. https://doi.org/10.1016/S2352-3026(21)00067-3
  1. Wendel S, Land K, Devine DV, Daly J, Bazin R, Tiberghien P ET AL. [Louw V 17th author]. Lessons learned in the collection of convalescent plasma during the COVID-19 pandemic. Vox Sang. 2021 Mar 27. https://doi.org/10.1111/vox.13096
  1. A Wonkam, K Lebeko, S Mowla, J J Noubiap, M Chong, G Pare.  Whole exome sequencing reveals a biallelic frameshift mutation in GRXCR2 in hearing impairment in Cameroon. Mol Genet Genomic Med. 2021 Mar 9. https://doi.org/10.1002/mgg3.1609
  1. Al-Riyami AZ, Louw VJ, Indrikovs AJ, Nedelcu E, Bakhtary S, Eichbaum QG, Smit Sibinga CT; Education Subcommittee of the AABB Global Transfusion Forum. Global survey of transfusion medicine curricula in medical schools: Challenges and opportunities. Transfusion. 2021 Feb;61(2):617-626. https://doi.org/10.1111/trf.16147
  1. G Godsmark, L Alves De Souza Rios, S Mowla.  Activation-Induced Cytidine Deaminase Promotes Proliferation and Enhances Chemo-resistance and Migration in B-cell Lymphoma. Anticancer Res. 2021 Jan;41(1):237-247. https://doi.org/10.21873/anticanres.14770

2020: 

  1. Antel K, Louw VJ, Maartens G, Oosthuizen J, Verburgh E. Diagnosing lymphoma in the shadow of an epidemic: lessons learned from the diagnostic challenges posed by the dual tuberculosis and HIV epidemics. Leuk Lymphoma. 2020 Dec;61(14):3417-3421. https://doi.org/10.1080/10428194.2020.1815016
  1. L Alves de Souza Rios, B Cloete, S Mowla.  Activation-induced cytidine deaminase: in sickness and in health. J Cancer Res Clin Oncol. 2020 Nov.  https://doi.org/10.1007/s00432-020-03348-x
  1. N Mdletshe, A Nel, K Shires, S Mowla.  HIV Nef enhances the expression of oncogenic c-MYC and activation-induced cytidine deaminase in Burkitt lymphoma cells, promoting genomic instability.  Infectious Agents and Cancer 2020 September.    https://doi.org/10.1186/s13027-020-00320-9
  1. Antel K, Chetty D, Oosthuizen J, Mohamed Z, Van der Vyver L, Verburgh E. CD68-positive tumour associated macrophages, PD-L1 expression, and EBV latent infection in a high HIV-prevalent South African cohort of Hodgkin lymphoma patients. Pathology. 2021 Aug;53(5):628-634. https://doi.org/10.1016/j.pathol.2020.11.004
  1. K Shires, A Rust.  Novel multiplex RT-PCR assay to detect BCR/ABL mRNA variants.  The Journal of Medical Laboratory Science & Technology South Africa 2020 July.  https://doi.org/10.36303/JMLSTSA.2020.2.1.15
  1. J Bailly, S Louw, A de Koker, JJC Potgieter, MJ Coetzee, ZC Chapanduka, JJ Opie.  Guidelines for lupus    anticoagulant testing in South Africa. The Journal of Medical Laboratory Science & Technology South Africa 2020 July.  https://doi.org/10.36303/JMLSTSA.2020.2.1.39
  1. Shein R, du Toit J, Goeijenbier M, du Toit C, Verburgh E. HIV-associated and idiopathic-acquired haemophilia A: A single-centre case series from Cape Town, South Africa. Neth J Med. 2020 Jul;78(4):196-201. https://pubmed.ncbi.nlm.nih.gov/32641545/
  1. K Shires, A Rust.  Novel multiplex RT-PCR assay to detect BCR/ABL mRNA variants.  The Journal of Medical Laboratory Science & Technology South Africa 2020 July.  https://doi.org/10.36303/JMLSTSA.2020.2.1.15
  1. Shander A, Goobie SM, Warner MA, Aapro M, Bisbe E, Perez-Calatayud AA et al. [Louw V 31st author]. International Foundation of Patient Blood Management (IFPBM) and Society for the Advancement of Blood Management (SABM) Work Group. Essential Role of Patient Blood Management in a Pandemic: A Call for Action. Anesth Analg. 2020 Jul;131(1):74-85. https://doi.org/10.1213/ANE.0000000000004844
  1. S Cassim, K Antel, D R Chetty, J Oosthuizen, J Opie, Z Mohamed, E Verburgh.  Diffuse large B-cell lymphoma in a South African cohort with a high HIV prevalence: an analysis by cell-of-origin, Epstein-Barr virus infection and survival. Pathology. 2020 Jun.  https://doi.org/10.1016/j.pathol.2020.02.007
  1. Van den Berg K, Vermeulen M, Glatt TN, Wasserman S, Barrett CL, Peter J, Brittain D, Louw VJ. COVID-19: Convalescent plasma as a potential therapy. S Afr Med J. 2020 Jun 4;110(7):562-563. http://dx.doi.org/10.7196/SAMJ.2020.v110i7.14983 
  1. M Kriel, A Davidson, K Pillay, M Hendricks, L Phillips.  Clinicopathologic Characterization of Children With B-Cell Non-Hodgkin Lymphoma Over 10 Years at a Tertiary Center in Cape Town, South Africa. J Pediatr Hematol Oncol. 2020 May.  https://doi.org/10.1097/MPH.0000000000001709
  1. Shein R, Mashigo N, du Toit CE, Oosthuizen J, Seftel MD, Louw VJ, Verburgh E. Outcomes for Patients With Acute Promyelocytic Leukemia in South Africa. Clin Lymphoma Myeloma Leuk. 2021 Apr;21(4):e348-e352. https://doi.org/10.1016/j.clml.2020.12.006
  1. Wise RD, Gibbs MW, Louw VJ. Lockdown and our national supply of blood products. S Afr Med J. 2020 Apr 2;110(5):12904. http://dx.doi.org/10.7196/samj.2020.v110i5.14749 
  1. Wise R, Bishop D, Gibbs M, Govender K, James M, Kabambi F, Louw V, et al. South African Society of Anaesthesiologists Perioperative Patient Blood Management Guidelines 2020. Southern African Journal of Anaesthesia and Analgesia 2020;26(6)(Supplement):S1-59. https://doi.org/10.36303/SAJAA.2020.26.6.S1%20
  1.  J Opie, K Antel, A Koller, N Novitzky.  In the South African setting, HIV-associated Burkitt lymphoma is associated with frequent leukaemic presentation, complex cytogenetic karyotypes, and adverse clinical outcomes. Ann Hematol. 2020 Mar.  https://doi.org/10.1007/s00277-020-03908-8
  1. Antel K, Oosthuizen J, Malherbe F, Louw VJ, Nicol MP, Maartens G, Verburgh E. Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis. BMC Infect Dis. 2020 Jan 13;20(1):33. doi: 10.1186/s12879-019-4749-x. Erratum in: BMC Infect Dis. 2020 Mar 2;20(1):187. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958753/
  1. J Bailly, B F Jacobson, S Louw.   A case series of Factor V Leiden mutation in pregnancy. S Afr J ObstetGynaecol2020.  http://www.sajog.org.za/index.php/SAJOG/article/view/1517/725
  1. Wonkam-Tingang E, Schrauwen I, Esoh KK, Bharadwaj T, Nouel-Saied LM, Acharya A, Nasir A, Adadey SM, Mowla S, Leal SM, et al. Bi-Allelic Novel Variants in CLIC5 Identified in a Cameroonian Multiplex Family with Non-Syndromic Hearing Impairment. Genes. 2020; 11(11):1249. https://doi.org/10.3390/genes11111249