2024

  1. Mkhize B, Court R, Castel S, Joubert A, van der Merwe M, Maartens G, Conradie F, Wiesner L. Validation and application of an online extraction and liquid chromatography tandem mass spectrometry assay for the analysis of delamanid and its DM-6705 metabolite in human breast milk. J Pharm Biomed Anal. 2024 May 16;246:116225. doi: 10.1016/j.jpba.2024.116225. Epub ahead of print. PMID: 38761519.
  2. Watson DJ, Laing L, Petzer JP, Wong HN, Parkinson CJ, Wiesner L, Haynes RK. Efficacies and ADME properties of redox active methylene blue and phenoxazine analogues for use in new antimalarial triple drug combinations with amino- artemisinins. Front Pharmacol. 2024 Jan 8;14:1308400. doi: 10.3389/fphar.2023.1308400. PMID: 38259296; PMCID: PMC10800708.
  3. Sydwell Poulo Maputla , Willem Van Dalen , Anton Joubert , Jennifer Norman , Sandra Castel , Marthinus van der Merwe , Lubbe Wiesner. A validated liquid chromatography-tandem mass spectrometry assay for the analysis of isoniazid and its metabolite acetyl-isoniazid in urine. Journal of Mass Spectrometry and Advances in the Clinical Lab 32 (2024) 11–17. https://doi.org/10.1016/j.jmsacl.2024.02.001

2023 

  1. Mazanhanga MT, Joubert A, Castel SA, van der Merwe M, Maartens G, Dooley KE, Upton CM, Wiesner L. Liquid chromatography-tandem mass spectrometry analysis of delamanid and its metabolite in human cerebrospinal fluid using protein precipitation and on-line solid-phase extraction. J Pharm Biomed Anal. 2023 Feb 3;227:115281. doi: 10.1016/j.jpba.2023.115281. Epub ahead of print. PMID: 36739721.
  2. Mkhize B, Court R, Castel S, Joubert A, van der Merwe M, Wiesner L. Development and validation of a liquid chromatography tandem mass spectrometry assay for the analysis of bedaquiline and M2 in breast milk. J Mass Spectrom Adv Clin Lab. 2023 Dec 13;31:8-16. doi: 10.1016/j.jmsacl.2023.12.001. PMID: 38188986; PMCID: PMC10770620.
  3. Daniel J. Watson, Lubbe Wiesner, Tlhalefo Matimela, Denzil Beukes and Paul R. Meyers. Tandem LC-MS Identification of Antitubercular Compounds in Zones of Growth Inhibition Produced by South African Filamentous Actinobacteria. Molecules 2023, 28(11), 4276. doi.org/10.3390/molecules28114276
  4. Marian Mazanhanga, Anton Joubert, Sandra Castel, Marthinus Van de Merwe, Gary Maartens, Sean Wasserman, Lubbe Wiesner. Validation of a quantitative liquid chromatography tandem mass spectrometry assay for linezolid in cerebrospinal fluid and its application to patients with HIV-associated TB-meningitis. Heliyon 9 (2023) e21962. doi.org/10.1016/j.heliyon.2023.e21962

2022

  1. Joubert A, Joubert A, van der Merwe M, Norman J, Castel S, Denti P, Sliwa K, Maartens G, Sinxadi P, Wiesner L. Validation of a quantitative multiplex LC-MS/MS assay of carvedilol, enalaprilat, and perindoprilat in dried blood spots from heart failure patients and its cross validation with a plasma assay. J Mass Spectrom Adv Clin Lab. 2022 Dec 12;27:7-17. doi: 10.1016/j.jmsacl.2022.12.003. PMID: 36568714; PMCID: PMC9772843.
  2. Watson DJ, Evans A, Blockman M, Wiesner L. Detection of karakin poisoning using a targeted mass spectrometric workflow. S Afr Med J. 2022 Dec 1;112(12):901-903. doi: 0.7196/SAMJ.2022.v112i12.16667. PMID: 36472319.
  3. Zuma P, Joubert A, van der Merwe M, Norman J, Waitt C, Court R, Loveday M, Castel S, Wiesner L. Validation and application of a quantitative LC-MS/MS assay for the analysis of first-line anti-tuberculosis drugs, rifabutin and their metabolites in human breast milk. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Nov 15;1211:123489. doi: 10.1016/j.jchromb.2022.123489. Epub 2022 Oct 4. PMID: 36215877.
  4. Watson DJ, Laing L, Beteck RM, Gibhard L, Haynes RK, Wiesner L. The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria. Front Pharmacol. 2022 Aug 19;13:957690. doi: 10.3389/fphar.2022.957690. PMID: 36091789; PMCID: PMC9450014.
  5. Mkhize B, Kellermann T, Norman J, Castel S, Joubert A, van der Merwe M, Dooley KE, Mathad JS, Wiesner L. Validation and application of a quantitative liquid chromatography tandem mass spectrometry assay for the analysis of rifapentine and 25-O-desacetyl rifapentine in human milk. J Pharm Biomed Anal. 2022 Jun 5;215:114774. doi: 10.1016/j.jpba.2022.114774. Epub 2022 Apr 16. PMID: 35462285; PMCID: PMC9871952.