The Mechanobiology Lab is funded through international and South African research grants.

Ongoing

  • Physical Cell Signatures in HIV–associated Burkitt Leukaemia and Lymphoma. NRF, 2023-2025
  • Biomimetic Hydrogels for Myocardial Infarction Therapy. UCT, 2022-2024
  • Computational Mechanobiology and Bioengineering towards Biomaterial and Cell Therapies for Myocardial Infarction and Heart Failure. Dr Leopold and Carmen Ellinger Stiftung, 2015-2025

Completed

  • Enhancing Stem Cell Therapy for Heart Failure Through Hydrogel Based Growth Factor Delivery. NRF, 2021-2023
  • Development of Electrospun Fibrous Scaffold Structures for Cardiovascular Graft Applications. AREF, 2021-2023
  • Multiscale Modelling of Intramyocardial Stem Cell Therapies for Myocardial Infarction. NRF, 2014-2017
  • Computational Modelling of Single Cell Mechanics for Non-communicable and Infectious Diseases. SAMRC, 2015-2018
  • Cell and Virus Mechanics towards Improved Understanding of Aetiology and Treatment of Diseases. NRF, 2015-2017
  • Capacity Building of Biomedical Engineering Training and Research. NICHE, 2015-2018
  • Teaching and Research Capacity Building in Biomedical Engineering. NICHE, 2015-2018
  • Biomedical Research in Cardiovascular Diseases. CHPC, 2014-2017
  • Optimising Engineered Hydrogels for Stem Cell Delivery and Differentiation in the Heart. NRF & DST India, 2014-2017
  • Computational and Experimental Cell Mechanics and Mechanobiology. BIS UK, TIA, UCT, 2013-2014
  • Modelling of Biodegradable Polymer Scaffolds for Cardiovascular Tissue Regeneration. Royal Society UK, 2012-2014
  • Cardiovascular MRI and Modelling. NRF, 2012-2014
  • Computational Mechanics and Electro-elasticity Towards Improved Understanding of the Biomechanics of Myocardial Infarction and the Development of Novel Therapies. CHPC Flagship Project, 2010-2013
  • Biointegration and Biocompatibility of Porous Bacterial Cellulose. VR & NRF, 2010-2012
  • Modelling of High-Performance Biomaterials and Medical Devices for Cardiovascular Applications. Royal Academy of Engineering UK, 2011-2012
  • High-performance Ultra-portable Diagnostic Ultrasound System for Cardiovascular Imaging. NRF & UCT, 2011
  • Biomechanics and Engineering in the Treatment of Cardiovascular Diseases. NRF, 2009-2011
  • Development of Standard Scaffolds for the Rational Design of Bioactive Materials for Tissue Regeneration. EU & DST Seed Funding, 2010
  • Development of Standard Scaffolds for the Rational Design of Bioactive Materials for Tissue Regeneration. EU & DST Seed Funding, 2009
  • In-vivo Loading Conditions of Fully Implanted Cardiac Rhythm Assist Devices. NRF, 2008-2010 (not accepted)
  • Tissue Regenerating Vascular Graft - Project Seed Funding. EU & DST, 2008
  • Finite Element Analysis of Knitted Nitinol Vascular Support Meshes. Kips Bay Medical Inc, 2008
  • Reinforcement of Blood Vessel Replacements. NRF, 2006-2008
  • Medtronic Research Grant to the University of Cape Town. Medtronic Inc, 1995-2008
  • Equipment for X-ray & Angiography Imaging Diagnostics. UCT & NRF, 2007
  • Development and Rapid Prototyping of Models for LVAD Liners and Heart Valves. NRF, 2003-2004