News | UCT Pharmacometrics

Lufina undertakes the 2024 Next Generation Scientist Internship

Lufina spent the past three months in Basel, Switzerland, working on a pharmacometrics methodology project at Novartis Pharmaceuticals, under the Next Generation Scientist program.

Cheers to our September graduates!

We celebrate not one, but two team members at this year’s September Health Science graduation.

How should rifabutin be dosed in children during HIV co-treatment with lopinavir/ritonavir?

Gebreyesus et al. have characterized the interaction between rifabutin and lopinavir/ritonavir in children to optimize rifabutin dosing during co-treatment.

What is the optimal prophylactic dosing regimen for cefazolin during on-pump cardiac surgery in children?

Gebreyesus et al. have characterized the pharmacokinetics of cefazolin in children during cardiac surgery with cardiopulmonary bypass (CPB) and investigated the optimal dosing regimen for prophylaxis of surgical site infections.

We are hiring!

Check out these exciting opportunities for joining our group in Cape Town!

Does alcohol use affect tuberculosis treatment?

In our most recent publication, Wijk et al. explored the effect of alcohol consumption and illicit drug use on the pharmacokinetics of first-line tuberculosis treatment.

Lufina receives the young scientist best presentation award

Lufina was awarded the young scientist best presentation award at the 26th PK/PD expert meeting held in Isny, Germany in March 2024.

Collaboration with World Health Organization presented at CROI2024: Simplifying Dosing by Harmonizing Weight-Band-Based Dosing Across Therapeutic Areas in Children

We explored the simplification of dosing for children by harmonizing weight band-based dosing across disease areas in collaboration with the WHO and GAP-f. The results were presented by Dr. Hylke Waalewijn at the CROI2024 in Denver.

We have new additions to our team!

We have recently had the pleasure of welcoming three new PhD students.

Post-discharge chemoprevention of malaria and other infections in children with severe anaemia

UCT pharmacometrics group are now overseeing the pharmacokinetic and pharmacodynamic sub-study of the post-discharge malaria chemoprevention II (PDMC II) trial.

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